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Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0b6a406f2deb41ea96cf45072af0e221

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

About this item

Full title

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-09, Vol.10 (1), p.4022-9, Article 4022

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Genomic instability pathways in colorectal cancer (CRC) have been extensively studied, but the role of retrotransposition in colorectal carcinogenesis remains poorly understood. Although retrotransposons are usually repressed, they become active in several human cancers, in particular those of the gastrointestinal tract. Here we characterize retrot...

Alternative Titles

Full title

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0b6a406f2deb41ea96cf45072af0e221

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0b6a406f2deb41ea96cf45072af0e221

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-11770-0

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