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Performance Comparison of Droplet Digital PCR and Next‐Generation Sequencing for Circulating Tumor DNA Detection in Non‐Metastatic Rectal Cancer
Author / Creator:Szeto, Säde ; Kytölä, Soili ; Erkan, Erdogan Pekcan ; Ahtiainen, Maarit ; Mecklin, Jukka‐Pekka ; Kuopio, Teijo ; Sallinen, Ville ; Lepistö, Anna ; Koskenvuo, Laura ; Renkonen‐Sinisalo, Laura ; Anttonen, Anu ; Heiskala, Kukka ; Tulokas, Sanni ; Mäkelä, Siru ; Wirta, Erkki‐Ville ; Tuunanen, Tuija ; Salminen, Tapio ; Ristimäki, Ari ; Seppälä, Toni T.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2025-05, Vol.14 (9), p.e70943-n/a
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Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer
Author / Creator:Kondelin, Johanna ; Salokas, Kari ; Saarinen, Lilli ; Ovaska, Kristian ; Rauanheimo, Heli ; Plaketti, Roosa‐Maria ; Hamberg, Jiri ; Liu, Xiaonan ; Yadav, Leena ; Gylfe, Alexandra E ; Cajuso, Tatiana ; Hänninen, Ulrika A ; Palin, Kimmo ; Ristolainen, Heikki ; Katainen, Riku ; Kaasinen, Eevi ; Tanskanen, Tomas ; Aavikko, Mervi ; Taipale, Minna ; Taipale, Jussi ; Renkonen‐Sinisalo, Laura ; Lepistö, Anna ; Koskensalo, Selja ; Böhm, Jan ; Mecklin, Jukka‐Pekka ; Ongen, Halit ; Dermitzakis, Emmanouil T ; Kilpivaara, Outi ; Vahteristo, Pia ; Turunen, Mikko ; Hautaniemi, Sampsa ; Tuupanen, Sari ; Karhu, Auli ; Välimäki, Niko ; Varjosalo, Markku ; Pitkänen, Esa ; Aaltonen, Lauri A
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2018-09, Vol.10 (9), p.1-n/a
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Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts
Author / Creator:Vasen, Hans F A ; Blanco, Ignacio ; Aktan-Collan, Katja ; Gopie, Jessica P ; Alonso, Angel ; Aretz, Stefan ; Bernstein, Inge ; Bertario, Lucio ; Burn, John ; Capella, Gabriel ; Colas, Chrystelle ; Engel, Christoph ; Frayling, Ian M ; Genuardi, Maurizio ; Heinimann, Karl ; Hes, Frederik J ; Hodgson, Shirley V ; Karagiannis, John A ; Lalloo, Fiona ; Lindblom, Annika ; Mecklin, Jukka-Pekka ; Møller, Pal ; Myrhoj, Torben ; Nagengast, Fokko M ; Parc, Yann ; Ponz de Leon, Maurizio ; Renkonen-Sinisalo, Laura ; Sampson, Julian R ; Stormorken, Astrid ; Sijmons, Rolf H ; Tejpar, Sabine ; Thomas, Huw J W ; Rahner, Nils ; Wijnen, Juul T ; Järvinen, Heikki Juhani ; Möslein, Gabriela
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2013-06, Vol.62 (6), p.812-823
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Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant ca...
Author / Creator:Blatter, Robert ; Tschupp, Benjamin ; Aretz, Stefan ; Bernstein, Inge ; Colas, Chrystelle ; Evans, D. Gareth ; Genuardi, Maurizio ; Hes, Frederik J. ; Hüneburg, Robert ; Järvinen, Heikki ; Lalloo, Fiona ; Moeslein, Gabriela ; Renkonen-Sinisalo, Laura ; Resta, Nicoletta ; Spier, Isabel ; Varvara, Dora ; Vasen, Hans ; Latchford, Andrew R. ; Heinimann, Karl
Publisher:New York: Nature Publishing Group US
Journal title:Genetics in medicine, 2020-09, Vol.22 (9), p.1524-1532
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Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
Author / Creator:Cajuso, Tatiana ; Sulo, Päivi ; Tanskanen, Tomas ; Katainen, Riku ; Taira, Aurora ; Hänninen, Ulrika A. ; Kondelin, Johanna ; Forsström, Linda ; Välimäki, Niko ; Aavikko, Mervi ; Kaasinen, Eevi ; Ristimäki, Ari ; Koskensalo, Selja ; Lepistö, Anna ; Renkonen-Sinisalo, Laura ; Seppälä, Toni ; Kuopio, Teijo ; Böhm, Jan ; Mecklin, Jukka-Pekka ; Kilpivaara, Outi ; Pitkänen, Esa ; Palin, Kimmo ; Aaltonen, Lauri A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4022-9, Article 4022
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Is there a need for neoadjuvant short-course radiotherapy in T3 rectal cancer with positive lymph node involvement? A single-center retrospective cohort study
Author / Creator:Räsänen, Minna ; Renkonen-Sinisalo, Laura ; Mustonen, Harri ; Lepistö, Anna
Publisher:England: BioMed Central Ltd
Journal title:World journal of surgical oncology, 2019-08, Vol.17 (1), p.139-139, Article 139
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Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer
Author / Creator:Gylfe, Alexandra E. ; Katainen, Riku ; Kondelin, Johanna ; Tanskanen, Tomas ; Cajuso, Tatiana ; Hänninen, Ulrika ; Taipale, Jussi ; Taipale, Minna ; Renkonen-Sinisalo, Laura ; Järvinen, Heikki ; Mecklin, Jukka-Pekka ; Kilpivaara, Outi ; Pitkänen, Esa ; Vahteristo, Pia ; Tuupanen, Sari ; Karhu, Auli ; Aaltonen, Lauri A.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2013-10, Vol.9 (10), p.e1003876-e1003876
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ArticlesPeer ReviewedFull Text
Pattern of rectal cancer recurrence after curative surgery
Author / Creator:Räsänen, Minna ; Carpelan-Holmström, Monika ; Mustonen, Harri ; Renkonen-Sinisalo, Laura ; Lepistö, Anna
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:International journal of colorectal disease, 2015-06, Vol.30 (6), p.775-785
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ArticlesPeer ReviewedFull Text
Structural features of somatic and germline retrotransposition events in humans
Author / Creator:Nummi, Päivi ; Cajuso, Tatiana ; Norri, Tuukka ; Taira, Aurora ; Kuisma, Heli ; Välimäki, Niko ; Lepistö, Anna ; Renkonen-Sinisalo, Laura ; Koskensalo, Selja ; Seppälä, Toni T. ; Ristimäki, Ari ; Tahkola, Kyösti ; Mattila, Anne ; Böhm, Jan ; Mecklin, Jukka-Pekka ; Siili, Emma ; Pasanen, Annukka ; Heikinheimo, Oskari ; Bützow, Ralf ; Karhu, Auli ; Burns, Kathleen H. ; Palin, Kimmo ; Aaltonen, Lauri A.
Publisher:England: BioMed Central Ltd
Journal title:Mobile DNA, 2025-04, Vol.16 (1), p.20-19, Article 20
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ArticlesPeer ReviewedFull Text
Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers
Author / Creator:Hänninen, Ulrika A ; Erkki-Ville, Wirta ; Katainen Riku ; Tanskanen Tomas ; Hamberg Jiri ; Taipale Minna ; Böhm, Jan ; Renkonen-Sinisalo Laura ; Lepistö, Anna ; sström, Linda M ; Pitkänen Esa ; Palin Kimmo ; Seppälä, Toni T ; Mäkinen Netta ; Jukka-Pekka, Mecklin ; Aaltonen, Lauri A
Publisher:London: Nature Publishing Group
Journal title:British journal of cancer, 2019-04, Vol.120 (9), p.922-930
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Fecal Microbiota Transplantation in Chronic Pouchitis: A Randomized, Parallel, Double-Blinded Clinical Trial
Author / Creator:Karjalainen, Essi K ; Renkonen-Sinisalo, Laura ; Satokari, Reetta ; Mustonen, Harri ; Ristimäki, Ari ; Arkkila, Perttu ; Lepistö, Anna H
Publisher:US: Oxford University Press
Journal title:Inflammatory bowel diseases, 2021-11, Vol.27 (11), p.1766-1772
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Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
Author / Creator:Møller, Pål ; Seppälä, Toni ; Bernstein, Inge ; Holinski-Feder, Elke ; Sala, Paola ; Evans, D Gareth ; Lindblom, Annika ; Macrae, Finlay ; Blanco, Ignacio ; Sijmons, Rolf ; Jeffries, Jacqueline ; Vasen, Hans ; Burn, John ; Nakken, Sigve ; Hovig, Eivind ; Rødland, Einar Andreas ; Tharmaratnam, Kukatharmini ; de Vos tot Nederveen Cappel, Wouter H ; Hill, James ; Wijnen, Juul ; Green, Kate ; Lalloo, Fiona ; Sunde, Lone ; Mints, Miriam ; Bertario, Lucio ; Pineda, Marta ; Navarro, Matilde ; Morak, Monika ; Renkonen-Sinisalo, Laura ; Frayling, Ian M ; Plazzer, John-Paul ; Pylvanainen, Kirsi ; Sampson, Julian R ; Capella, Gabriel ; Mecklin, Jukka-Pekka ; Möslein, Gabriela
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2017-03, Vol.66 (3), p.464-472
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Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
Author / Creator:Møller, Pål ; Seppälä, Toni T ; Bernstein, Inge ; Holinski-Feder, Elke ; Sala, Paulo ; Gareth Evans, D ; Lindblom, Annika ; Macrae, Finlay ; Blanco, Ignacio ; Sijmons, Rolf H ; Jeffries, Jacqueline ; Vasen, Hans F A ; Burn, John ; Nakken, Sigve ; Hovig, Eivind ; Rødland, Einar Andreas ; Tharmaratnam, Kukatharmini ; de Vos tot Nederveen Cappel, Wouter H ; Hill, James ; Wijnen, Juul T ; Jenkins, Mark A ; Green, Kate ; Lalloo, Fiona ; Sunde, Lone ; Mints, Miriam ; Bertario, Lucio ; Pineda, Marta ; Navarro, Matilde ; Morak, Monika ; Renkonen-Sinisalo, Laura ; Valentin, Mev Dominguez ; Frayling, Ian M ; Plazzer, John-Paul ; Pylvanainen, Kirsi ; Genuardi, Maurizio ; Mecklin, Jukka-Pekka ; Moeslein, Gabriela ; Sampson, Julian R ; Capella, Gabriel
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2018-07, Vol.67 (7), p.1306-1316
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Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
Author / Creator:Møller, Pål ; Seppälä, Toni ; Bernstein, Inge ; Holinski-Feder, Elke ; Sala, Paola ; Evans, D Gareth ; Lindblom, Annika ; Macrae, Finlay ; Blanco, Ignacio ; Sijmons, Rolf ; Jeffries, Jacqueline ; Vasen, Hans ; Burn, John ; Nakken, Sigve ; Hovig, Eivind ; Rødland, Einar Andreas ; Tharmaratnam, Kukatharmini ; de Vos tot Nederveen Cappel, Wouter H ; Hill, James ; Wijnen, Juul ; Jenkins, Mark ; Green, Kate ; Lalloo, Fiona ; Sunde, Lone ; Mints, Miriam ; Bertario, Lucio ; Pineda, Marta ; Navarro, Matilde ; Morak, Monika ; Renkonen-Sinisalo, Laura ; Frayling, Ian M ; Plazzer, John-Paul ; Pylvanainen, Kirsi ; Genuardi, Maurizio ; Mecklin, Jukka-Pekka ; Möslein, Gabriela ; Sampson, Julian R ; Capella, Gabriel
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2017-09, Vol.66 (9), p.1657-1664
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Molecular changes preceding endometrial and ovarian cancer: a study of consecutive endometrial specimens from Lynch syndrome surveillance
Author / Creator:Niskakoski, Anni ; Pasanen, Annukka ; Lassus, Heini ; Renkonen-Sinisalo, Laura ; Kaur, Sippy ; Mecklin, Jukka-Pekka ; Bützow, Ralf ; Peltomäki, Päivi
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2018-08, Vol.31 (8), p.1291-1301
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Peutz–Jeghers syndrome: a systematic review and recommendations for management
Author / Creator:Beggs, A D ; Latchford, A R ; Vasen, H F A ; Moslein, G ; Alonso, A ; Aretz, S ; Bertario, L ; Blanco, I ; Bülow, S ; Burn, J ; Capella, G ; Colas, C ; Friedl, W ; Møller, P ; Hes, F J ; Järvinen, H ; Mecklin, J-P ; Nagengast, F M ; Parc, Y ; Phillips, R K S ; Hyer, W ; Ponz de Leon, M ; Renkonen-Sinisalo, L ; Sampson, J R ; Stormorken, A ; Tejpar, S ; Thomas, H J W ; Wijnen, J T ; Clark, S K ; Hodgson, S V
Publisher:London: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2010-07, Vol.59 (7), p.975-986
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Author’s Reply: Fecal Microbiota Transplantation for Chronic Pouchitis: Promising Novel Therapeutic or Lost Cause?
Author / Creator:Karjalainen, Essi K ; Renkonen-Sinisalo, Laura ; Satokari, Reetta ; Mustonen, Harri ; Ristimäki, Ari ; Arkkila, Perttu ; Lepistö, Anna H
Publisher:US: Oxford University Press
Journal title:Inflammatory bowel diseases, 2021-07, Vol.27 (7), p.e79-e80
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Guidelines for the clinical management of familial adenomatous polyposis (FAP)
Author / Creator:Vasen, H F A ; Möslein, G ; Alonso, A ; Aretz, S ; Bernstein, I ; Bertario, L ; Blanco, I ; Bülow, S ; Burn, J ; Capella, G ; Colas, C ; Engel, C ; Frayling, I ; Friedl, W ; Hes, F J ; Hodgson, S ; Järvinen, H ; Mecklin, J-P ; Møller, P ; Myrhøi, T ; Nagengast, F M ; Parc, Y ; Phillips, R ; Clark, S K ; de Leon, M Ponz ; Renkonen-Sinisalo, L ; Sampson, J R ; Stormorken, A ; Tejpar, S ; Thomas, H J W ; Wijnen, J
Publisher:London: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2008-05, Vol.57 (5), p.704-713
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Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (vol 55, pg 89, 2023)
Author / Creator:Fernandez-Rozadilla, C ; Timofeeva, M ; Chen, Z ; Law, P ; Thomas, M ; Schmit, S ; Diez-Obrero, V ; Hsu, L ; Fernandez-Tajes, J ; Palles, C
Journal title:NATURE GENETICS, 2023-03, Vol.55 (3), p.519
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Contribution of allelic imbalance to colorectal cancer
Author / Creator:Palin, Kimmo ; Pitkänen, Esa ; Turunen, Mikko ; Sahu, Biswajyoti ; Pihlajamaa, Päivi ; Kivioja, Teemu ; Kaasinen, Eevi ; Välimäki, Niko ; Hänninen, Ulrika A ; Cajuso, Tatiana ; Aavikko, Mervi ; Tuupanen, Sari ; Kilpivaara, Outi ; van den Berg, Linda ; Kondelin, Johanna ; Tanskanen, Tomas ; Katainen, Riku ; Grau, Marta ; Rauanheimo, Heli ; Roosa-Maria Plaketti ; Taira, Aurora ; Sulo, Päivi ; Hartonen, Tuomo ; Kashyap, Dave ; Schmierer, Bernhard ; Botla, Sandeep ; Sokolova, Maria ; Vähärautio, Anna ; Gladysz, Kornelia ; Ongen, Halit ; Dermitzakis, Emmanouil ; Jesper Bertram Bramsen ; Torben Falck Ørntoft ; Andersen, Claus Lindbjerg ; Ristimäki, Ari ; Lepistö, Anna ; Renkonen-Sinisalo, Laura ; Jukka-Pekka Mecklin ; Taipale, Jussi ; Aaltonen, Lauri A
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2018-09, Vol.9, p.1-9
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Performance Comparison of Droplet Digital PCR and Next‐Generation Sequencing for Circulating Tumor DNA Detection in Non‐Metastatic Rectal Cancer

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Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer

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Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

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Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant ca...

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Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

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Is there a need for neoadjuvant short-course radiotherapy in T3 rectal cancer with positive lymph node involvement? A single-center retrospective cohort study

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Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer

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Pattern of rectal cancer recurrence after curative surgery

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Structural features of somatic and germline retrotransposition events in humans

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Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers

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Fecal Microbiota Transplantation in Chronic Pouchitis: A Randomized, Parallel, Double-Blinded Clinical Trial

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Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database

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Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

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Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database

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Molecular changes preceding endometrial and ovarian cancer: a study of consecutive endometrial specimens from Lynch syndrome surveillance

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Peutz–Jeghers syndrome: a systematic review and recommendations for management

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Author’s Reply: Fecal Microbiota Transplantation for Chronic Pouchitis: Promising Novel Therapeutic or Lost Cause?

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Guidelines for the clinical management of familial adenomatous polyposis (FAP)

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Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (vol 55, pg 89, 2023)

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Contribution of allelic imbalance to colorectal cancer

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