High diagnostic performance of independent alpha-synuclein seed amplification assays for detection o...
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease
About this item
Full title
Author / Creator
Russo, Marco J , Orru, Christina D , Concha-Marambio, Luis , Giaisi, Simone , Groveman, Bradley R , Farris, Carly M , Holguin, Bret , Hughson, Andrew G , LaFontant, David-Erick , Caspell-Garcia, Chelsea , Coffey, Christopher S , Mollon, Jennifer , Hutten, Samantha J , Merchant, Kalpana , Heym, Roland G , Soto, Claudio , Caughey, Byron and Kang, Un Jung
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Alpha-synuclein seed amplification assays (αSyn-SAAs) are promising diagnostic tools for Parkinson's disease (PD) and related synucleinopathies. They enable detection of seeding-competent alpha-synuclein aggregates in living patients and have shown high diagnostic accuracy in several PD and other synucleinopathy patient cohorts. However, there has...
Alternative Titles
Full title
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease
Authors, Artists and Contributors
Author / Creator
Orru, Christina D
Concha-Marambio, Luis
Giaisi, Simone
Groveman, Bradley R
Farris, Carly M
Holguin, Bret
Hughson, Andrew G
LaFontant, David-Erick
Caspell-Garcia, Chelsea
Coffey, Christopher S
Mollon, Jennifer
Hutten, Samantha J
Merchant, Kalpana
Heym, Roland G
Soto, Claudio
Caughey, Byron
Kang, Un Jung
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0bfa462724b04d9e816718abf0d9ecbe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0bfa462724b04d9e816718abf0d9ecbe
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-021-01282-8
