Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tu...
Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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It has been postulated that imprinting aberrations are common in tumors. To understand the role of imprinting in cancer, we have characterized copy-number and methylation in over 280 cancer cell lines and confirm our observations in primary tumors. Imprinted differentially methylated regions (DMRs) regulate parent-of-origin monoallelic expression o...
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Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors
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TN_cdi_doaj_primary_oai_doaj_org_article_0ced9395b01e4ea4b12aeea8da2c0e0e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0ced9395b01e4ea4b12aeea8da2c0e0e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00639-9
