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Long‐term response to osimertinib in elderly patients with lung adenocarcinoma harbouring de novo EG...

Long‐term response to osimertinib in elderly patients with lung adenocarcinoma harbouring de novo EG...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0cedb960beee460a9f83e1aa6f61dd01

Long‐term response to osimertinib in elderly patients with lung adenocarcinoma harbouring de novo EGFR T790M: a case report and literature review

About this item

Full title

Long‐term response to osimertinib in elderly patients with lung adenocarcinoma harbouring de novo EGFR T790M: a case report and literature review

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

Respirology Case Reports, 2021-06, Vol.9 (6), p.e00759-n/a

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Osimertinib is a potent and irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that selectively acts on both EGFR‐sensitive and EGFR T790M‐resistant mutations. Patients with pre‐treatment EGFR T790M mutations (de novo EGFR T790M) respond poorly to existing EGFR‐TKIs, whereas osimertinib has positive effects. Howeve...

Alternative Titles

Full title

Long‐term response to osimertinib in elderly patients with lung adenocarcinoma harbouring de novo EGFR T790M: a case report and literature review

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0cedb960beee460a9f83e1aa6f61dd01

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0cedb960beee460a9f83e1aa6f61dd01

Other Identifiers

ISSN

2051-3380

E-ISSN

2051-3380

DOI

10.1002/rcr2.759

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