Actin-microtubule interplay coordinates spindle assembly in human oocytes
Actin-microtubule interplay coordinates spindle assembly in human oocytes
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mammalian oocytes assemble a bipolar acentriolar microtubule spindle to segregate chromosomes during asymmetric division. There is increasing evidence that actin in the spindle interior not only participates in spindle migration and positioning but also protects oocytes from chromosome segregation errors leading to aneuploidy. Here we show that act...
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Actin-microtubule interplay coordinates spindle assembly in human oocytes
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TN_cdi_doaj_primary_oai_doaj_org_article_0d78517a7967400c8c82dd20c8e27f04
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d78517a7967400c8c82dd20c8e27f04
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12674-9