Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug r...
Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance
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Author / Creator
Wang, Hai , Liang, Yutong , Yin, Yue , Zhang, Jie , Su, Wen , White, Alisa M. , Bin Jiang , Xu, Jiangsheng , Zhang, Yuntian , Stewart, Samantha , Lu, Xiongbin and He, Xiaoming
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
The transmembrane P-glycoprotein (P-gp) pumps that efflux drugs are a major mechanism of cancer drug resistance. They are also important in protecting normal tissue cells from poisonous xenobiotics and endogenous metabolites. Here, we report a fucoidan-decorated silica-carbon nano-onion (FSCNO) hybrid nanoparticle that targets tumor vasculature to...
Alternative Titles
Full title
Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance
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TN_cdi_doaj_primary_oai_doaj_org_article_0dcc96fe3e8f47d092bab3e71efd82f3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0dcc96fe3e8f47d092bab3e71efd82f3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20588-0
