Co-occurring expression and methylation QTLs allow detection of common causal variants and shared bi...
Co-occurring expression and methylation QTLs allow detection of common causal variants and shared biological mechanisms
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Inherited genetic variation affects local gene expression and DNA methylation in humans. Most expression quantitative trait loci (
cis
-eQTLs) occur at the same genomic location as a methylation QTL (
cis
-meQTL), suggesting a common causal variant and shared mechanism. Using DNA and RNA from peripheral blood of Bangladeshi individuals,...
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Co-occurring expression and methylation QTLs allow detection of common causal variants and shared biological mechanisms
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TN_cdi_doaj_primary_oai_doaj_org_article_0e237f531ba64865aebc696a3861462b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e237f531ba64865aebc696a3861462b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03209-9
