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GraphMHC: Neoantigen prediction model applying the graph neural network to molecular structure

GraphMHC: Neoantigen prediction model applying the graph neural network to molecular structure

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e2e7373bec94ec09aa483e8a23c2e92

GraphMHC: Neoantigen prediction model applying the graph neural network to molecular structure

About this item

Full title

GraphMHC: Neoantigen prediction model applying the graph neural network to molecular structure

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-03, Vol.19 (3), p.e0291223-e0291223

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Neoantigens are tumor-derived peptides and are biomarkers that can predict prognosis related to immune checkpoint inhibition by estimating their binding to major histocompatibility complex (MHC) proteins. Although deep neural networks have been primarily used for these prediction models, it is difficult to interpret the models reported thus far as...

Alternative Titles

Full title

GraphMHC: Neoantigen prediction model applying the graph neural network to molecular structure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0e2e7373bec94ec09aa483e8a23c2e92

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e2e7373bec94ec09aa483e8a23c2e92

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0291223

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