EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer
EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer
About this item
Full title
Author / Creator
Wang, Li , Saci, Abdel , Szabo, Peter M. , Chasalow, Scott D. , Castillo-Martin, Mireia , Domingo-Domenech, Josep , Siefker-Radtke, Arlene , Sharma, Padmanee , Sfakianos, John P. , Gong, Yixuan , Dominguez-Andres, Ana , Oh, William K. , Mulholland, David , Azrilevich, Alex , Hu, Liangyuan , Cordon-Cardo, Carlos , Salmon, Hélène , Bhardwaj, Nina , Zhu, Jun and Galsky, Matthew D.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cancers infiltrated with T-cells are associated with a higher likelihood of response to PD-1/PD-L1 blockade. Counterintuitively, a correlation between epithelial–mesenchymal transition (EMT)-related gene expression and T-cell infiltration has been observed across tumor types. Here we demonstrate, using The Cancer Genome Atlas (TCGA) urothelial canc...
Alternative Titles
Full title
EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer
Authors, Artists and Contributors
Author / Creator
Saci, Abdel
Szabo, Peter M.
Chasalow, Scott D.
Castillo-Martin, Mireia
Domingo-Domenech, Josep
Siefker-Radtke, Arlene
Sharma, Padmanee
Sfakianos, John P.
Gong, Yixuan
Dominguez-Andres, Ana
Oh, William K.
Mulholland, David
Azrilevich, Alex
Hu, Liangyuan
Cordon-Cardo, Carlos
Salmon, Hélène
Bhardwaj, Nina
Zhu, Jun
Galsky, Matthew D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0e94d49acf9b403fa3f22b69087eb769
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e94d49acf9b403fa3f22b69087eb769
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05992-x
