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Sharma, Padmanee
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: SAR-SOK, 2022, p.10340-10340
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Sharma, Padmanee
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: SAV-SOP, 2021, p.10311-10311
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ArticlesPeer ReviewedFull Text
Dissecting the mechanisms of immune checkpoint therapy
Author / Creator:Sharma, Padmanee ; Allison, James P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2020-02, Vol.20 (2), p.75-76
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The future of immune checkpoint therapy
Author / Creator:Sharma, Padmanee ; Allison, James P.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-04, Vol.348 (6230), p.56-61
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Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma
Author / Creator:Goswami, Sangeeta ; Walle, Thomas ; Cornish, Andrew E. ; Basu, Sreyashi ; Anandhan, Swetha ; Fernandez, Irina ; Vence, Luis ; Blando, Jorge ; Zhao, Hao ; Yadav, Shalini Singh ; Ott, Martina ; Kong, Ling Y. ; Heimberger, Amy B. ; de Groot, John ; Sepesi, Boris ; Overman, Michael ; Kopetz, Scott ; Allison, James P. ; Pe’er, Dana ; Sharma, Padmanee
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-01, Vol.26 (1), p.39-46
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Nivolumab in metastatic urothelial carcinoma after platinum therapy (CheckMate 275): a multicentre, single-arm, phase 2 trial
Author / Creator:Sharma, Padmanee, Prof ; Retz, Margitta, Prof ; Siefker-Radtke, Arlene, MD ; Baron, Ari, MD ; Necchi, Andrea, MD ; Bedke, Jens, Prof ; Plimack, Elizabeth R, MD ; Vaena, Daniel, MD ; Grimm, Marc-Oliver, Prof ; Bracarda, Sergio, MD ; Arranz, José Ángel, MD ; Pal, Sumanta, MD ; Ohyama, Chikara, Prof ; Saci, Abdel, PhD ; Qu, Xiaotao, PhD ; Lambert, Alexandre, PhD ; Krishnan, Suba, MD ; Azrilevich, Alex, PharmD ; Galsky, Matthew D, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-03, Vol.18 (3), p.312-322
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ArticlesPeer ReviewedFull Text
Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial
Author / Creator:Sharma, Padmanee, Prof ; Callahan, Margaret K, MD ; Bono, Petri, MD ; Kim, Joseph, MD ; Spiliopoulou, Pavlina, MD ; Calvo, Emiliano, MD ; Pillai, Rathi N, MD ; Ott, Patrick A, MD ; de Braud, Filippo, Prof ; Morse, Michael, Prof ; Le, Dung T, MD ; Jaeger, Dirk, MD ; Chan, Emily, MD ; Harbison, Chris, PhD ; Lin, Chen-Sheng, PhD ; Tschaika, Marina, MD ; Azrilevich, Alex, PharmD ; Rosenberg, Jonathan E, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-11, Vol.17 (11), p.1590-1598
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Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy
Author / Creator:Abbas, Hussein A. ; Hao, Dapeng ; Tomczak, Katarzyna ; Barrodia, Praveen ; Im, Jin Seon ; Reville, Patrick K. ; Alaniz, Zoe ; Wang, Wei ; Wang, Ruiping ; Wang, Feng ; Al-Atrash, Gheath ; Takahashi, Koichi ; Ning, Jing ; Ding, Maomao ; Beird, Hannah C. ; Mathews, Jairo T. ; Little, Latasha ; Zhang, Jianhua ; Basu, Sreyashi ; Konopleva, Marina ; Marques-Piubelli, Mario L. ; Solis, Luisa M. ; Parra, Edwin Roger ; Lu, Wei ; Tamegnon, Auriole ; Garcia-Manero, Guillermo ; Green, Michael R. ; Sharma, Padmanee ; Allison, James P. ; Kornblau, Steven M. ; Rai, Kunal ; Wang, Linghua ; Daver, Naval ; Futreal, Andrew
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-10, Vol.12 (1), p.6071-13, Article 6071
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Effective combinatorial immunotherapy for castration-resistant prostate cancer
Author / Creator:Lu, Xin ; Horner, James W. ; Paul, Erin ; Shang, Xiaoying ; Troncoso, Patricia ; Deng, Pingna ; Jiang, Shan ; Chang, Qing ; Spring, Denise J. ; Sharma, Padmanee ; Zebala, John A. ; Maeda, Dean Y. ; Wang, Y. Alan ; DePinho, Ronald A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-03, Vol.543 (7647), p.728-732
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Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma
Author / Creator:Gao, Jianjun ; Navai, Neema ; Alhalabi, Omar ; Siefker-Radtke, Arlene ; Campbell, Matthew T. ; Tidwell, Rebecca Slack ; Guo, Charles C. ; Kamat, Ashish M. ; Matin, Surena F. ; Araujo, John C. ; Shah, Amishi Y. ; Msaouel, Pavlos ; Corn, Paul ; Wang, Jianbo ; Papadopoulos, John N. ; Yadav, Shalini S. ; Blando, Jorge M. ; Duan, Fei ; Basu, Sreyashi ; Liu, Wenbin ; Shen, Yu ; Zhang, Yuwei ; Macaluso, Marc Daniel ; Wang, Ying ; Chen, Jianfeng ; Zhang, Jianhua ; Futreal, Andrew ; Dinney, Colin ; Allison, James P. ; Goswami, Sangeeta ; Sharma, Padmanee
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-12, Vol.26 (12), p.1845-1851
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ArticlesPeer ReviewedFull Text
EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer
Author / Creator:Wang, Li ; Saci, Abdel ; Szabo, Peter M. ; Chasalow, Scott D. ; Castillo-Martin, Mireia ; Domingo-Domenech, Josep ; Siefker-Radtke, Arlene ; Sharma, Padmanee ; Sfakianos, John P. ; Gong, Yixuan ; Dominguez-Andres, Ana ; Oh, William K. ; Mulholland, David ; Azrilevich, Alex ; Hu, Liangyuan ; Cordon-Cardo, Carlos ; Salmon, Hélène ; Bhardwaj, Nina ; Zhu, Jun ; Galsky, Matthew D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3503-12, Article 3503
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ArticlesPeer ReviewedFull Text
Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis
Author / Creator:Wang, Yinghong ; Wiesnoski, Diana H. ; Helmink, Beth A. ; Gopalakrishnan, Vancheswaran ; Choi, Kati ; DuPont, Hebert L. ; Jiang, Zhi-Dong ; Abu-Sbeih, Hamzah ; Sanchez, Christopher A. ; Chang, Chia-Chi ; Parra, Edwin R. ; Francisco-Cruz, Alejandro ; Raju, Gottumukkala S. ; Stroehlein, John R. ; Campbell, Matthew T. ; Gao, Jianjun ; Subudhi, Sumit K. ; Maru, Dipen M. ; Blando, Jorge M. ; Lazar, Alexander J. ; Allison, James P. ; Sharma, Padmanee ; Tetzlaff, Michael T. ; Wargo, Jennifer A. ; Jenq, Robert R.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-12, Vol.24 (12), p.1804-1808
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Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer
Author / Creator:Blando, Jorge ; Sharma, Anu ; Higa, Maria Gisela ; Zhao, Hao ; Vence, Luis ; Yadav, Shalini S. ; Kim, Jiseong ; Sepulveda, Alejandro M. ; Sharp, Michael ; Maitra, Anirban ; Wargo, Jennifer ; Tetzlaff, Michael ; Broaddus, Russell ; Katz, Matthew H. G. ; Varadhachary, Gauri R. ; Overman, Michael ; Wang, Huamin ; Yee, Cassian ; Bernatchez, Chantale ; Iacobuzio-Donahue, Christine ; Basu, Sreyashi ; Allison, James P. ; Sharma, Padmanee
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (5), p.1692-1697
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Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma
Author / Creator:Campbell, Matthew T. ; Matin, Surena F. ; Tam, Alda L. ; Sheth, Rahul A. ; Ahrar, Kamran ; Tidwell, Rebecca S. ; Rao, Priya ; Karam, Jose A. ; Wood, Christopher G. ; Tannir, Nizar M. ; Jonasch, Eric ; Gao, Jianjun ; Zurita, Amado J. ; Shah, Amishi Y. ; Jindal, Sonali ; Duan, Fei ; Basu, Sreyashi ; Chen, Hong ; Espejo, Alexsandra B. ; Allison, James P. ; Yadav, Shalini S. ; Sharma, Padmanee
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6375-12, Article 6375
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Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial
Author / Creator:Antonia, Scott J, Prof ; López-Martin, José A, MD ; Bendell, Johanna, MD ; Ott, Patrick A, MD ; Taylor, Matthew, MD ; Eder, Joseph Paul, MD ; Jäger, Dirk, MD ; Pietanza, M Catherine, MD ; Le, Dung T, MD ; de Braud, Filippo, Prof ; Morse, Michael A, Prof ; Ascierto, Paolo A, MD ; Horn, Leora, MD ; Amin, Asim, MD ; Pillai, Rathi N, MD ; Evans, Jeffry, Prof ; Chau, Ian, MD ; Bono, Petri, MD ; Atmaca, Akin, MD ; Sharma, Padmanee, Prof ; Harbison, Christopher T, PhD ; Lin, Chen-Sheng, PhD ; Christensen, Olaf, MD ; Calvo, Emiliano, Dr
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-07, Vol.17 (7), p.883-895
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Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
Author / Creator:Zamarin, Dmitriy ; Holmgaard, Rikke B. ; Ricca, Jacob ; Plitt, Tamar ; Palese, Peter ; Sharma, Padmanee ; Merghoub, Taha ; Wolchok, Jedd D. ; Allison, James P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.14340-14340, Article 14340
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Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study
Author / Creator:Morris, Van K, MD ; Salem, Mohamed E, MD ; Nimeiri, Halla, MD ; Iqbal, Syma, MD ; Singh, Preet, MD ; Ciombor, Kristen, MD ; Polite, Blase, MD ; Deming, Dustin, MD ; Chan, Emily, MD ; Wade, James L, MD ; Xiao, Lianchun, MS ; Bekaii-Saab, Tanios, Prof ; Vence, Luis, PhD ; Blando, Jorge, DVM ; Mahvash, Armeen, MD ; Foo, Wai Chin, MD ; Ohaji, Chimela, MD ; Pasia, Manolo, BSN ; Bland, Gail, BS ; Ohinata, Aki, PAC ; Rogers, Jane, PharmD ; Mehdizadeh, Amir, MA ; Banks, Kimberly, MS ; Lanman, Richard, MD ; Wolff, Robert A, Prof ; Streicher, Howard, MD ; Allison, James, Prof ; Sharma, Padmanee, Prof ; Eng, Cathy, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-04, Vol.18 (4), p.446-453
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ArticlesPeer ReviewedFull Text
ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis
Author / Creator:Herbrich, Shelley ; Chaib, Mehdi ; Sharma, Padmanee
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2025-03, Vol.13 (3), p.e011564
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Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
Author / Creator:Shi, Lewis Zhichang ; Fu, Tihui ; Guan, Baoxiang ; Chen, Jianfeng ; Blando, Jorge M. ; Allison, James P. ; Xiong, Liangwen ; Subudhi, Sumit K. ; Gao, Jianjun ; Sharma, Padmanee
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-08, Vol.7 (1), p.12335-12335, Article 12335
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Defining unique clinical hallmarks for immune checkpoint inhibitor-based therapies
Author / Creator:Michielin, Olivier ; Lalani, Aly-Khan ; Robert, Caroline ; Sharma, Padmanee ; Peters, Solange
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-01, Vol.10 (1), p.e003024
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Sharma, Padmanee

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Sharma, Padmanee

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Dissecting the mechanisms of immune checkpoint therapy

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The future of immune checkpoint therapy

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Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma

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Nivolumab in metastatic urothelial carcinoma after platinum therapy (CheckMate 275): a multicentre, single-arm, phase 2 trial

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Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial

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Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy

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Effective combinatorial immunotherapy for castration-resistant prostate cancer

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Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma

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EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer

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Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

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Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer

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Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma

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Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial

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Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity

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Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study

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ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis

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Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy

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Defining unique clinical hallmarks for immune checkpoint inhibitor-based therapies

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