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Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treat...

Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f4cd09bfde34a258b2bc0068c98dce9

Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study

About this item

Full title

Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2011-07, Vol.11 (1), p.313-313, Article 313

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

This phase 1b study assessed the maximum tolerated dose (MTD), safety, and pharmacokinetics of motesanib (a small-molecule antagonist of VEGF receptors 1, 2, and 3; platelet-derived growth factor receptor; and Kit) administered once daily (QD) or twice daily (BID) in combination with erlotinib and gemcitabine in patients with solid tumors.
Patie...

Alternative Titles

Full title

Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0f4cd09bfde34a258b2bc0068c98dce9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f4cd09bfde34a258b2bc0068c98dce9

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/1471-2407-11-313

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