NLRP10 maintains epidermal homeostasis by promoting keratinocyte survival and P63-dependent differen...
NLRP10 maintains epidermal homeostasis by promoting keratinocyte survival and P63-dependent differentiation and barrier function
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Author / Creator
Cho, Yeonhee , Cao, Zhongzheng , Luo, Xin , Tian, Jennifer J. , Hukkanen, Renee R. , Hussien, Rajaa , Cancilla, Belinda , Chowdhury, Priyanka , Li, Fei , Ma, Shining , LaGory, Edward L. , Schroeder, Mark , Dusenberry, Amanda , Marshall, Leslie , Hawkins, Jenn , van Lookeren Campagne, Menno and Zhou, Yi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Atopic dermatitis (AD) is a common chronic inflammatory skin disorder characterized by disrupted epidermal barrier function and aberrant immune responses. Despite recent developments in new therapeutics for AD, there is still a large unmet medical need for disease management due to the complex and multifactorial nature of AD. Recent genome-wide ass...
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Full title
NLRP10 maintains epidermal homeostasis by promoting keratinocyte survival and P63-dependent differentiation and barrier function
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TN_cdi_doaj_primary_oai_doaj_org_article_0f6996b847b149ec9c63d80d500d59ad
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f6996b847b149ec9c63d80d500d59ad
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-07146-y
