HNF1A regulates colorectal cancer progression and drug resistance as a downstream of POU5F1
HNF1A regulates colorectal cancer progression and drug resistance as a downstream of POU5F1
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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POU5F1-expressing cells can self-renew and differentiate, contributing to metastasis formation in colorectal cancer (CRC), but it plays an important role in normal pluripotent stem cells. Here, we identified the CRC-specific gene, HNF1A, which is the downstream of POU5F1. HNF1A associates with fatty acid and glucose metabolism, and CRC cells highly...
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HNF1A regulates colorectal cancer progression and drug resistance as a downstream of POU5F1
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TN_cdi_doaj_primary_oai_doaj_org_article_0f85e71fae9941418cd4c2ed466a26cd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f85e71fae9941418cd4c2ed466a26cd
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-89126-2
