Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing herit...
Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Despite the success of genome-wide association studies, much of the genetic contribution to complex traits remains unexplained. Here, we analyse high coverage whole-genome sequencing data, to evaluate the contribution of rare genetic variants to 414 plasma proteins. The frequency distribution of genetic variants is skewed towards the rare spectrum,...
Alternative Titles
Full title
Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1070fe1cf0884dc9a1fe9d7ebf5b6af9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1070fe1cf0884dc9a1fe9d7ebf5b6af9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30208-8
