A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultrace...
A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultracentrifugation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Two-cycle cesium chloride (2 × CsCl) gradient ultracentrifugation is a conventional approach for purifying recombinant adenoviruses (rAds) for research purposes (gene therapy, vaccines, and oncolytic vectors). However, rAds containing the RGD-4C peptide in the HI loop of the fiber knob domain tend to aggregate during 2 × CsCl gradient ultracentrifu...
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A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultracentrifugation
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TN_cdi_doaj_primary_oai_doaj_org_article_10edaa59e24f4ba993cb64ff48bcec17
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_10edaa59e24f4ba993cb64ff48bcec17
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-94573-y
