Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through...
Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC
About this item
Full title
Author / Creator
Sena, Laura A , Kumar, Rajendra , Sanin, David E , Thompson, Elizabeth A , Rosen, D Marc , Dalrymple, Susan L , Antony, Lizamma , Yang, Yuhan , Gomes-Alexandre, Carolina , Hicks, Jessica L , Jones, Tracy , Bowers, Kiara A , Eskra, Jillian N , Meyers, Jennifer , Gupta, Anuj , Skaist, Alyza , Yegnasubramanian, Srinivasan , Luo, Jun , Brennen, W Nathaniel , Kachhap, Sushant K , Antonarakis, Emmanuel S , De Marzo, Angelo M , Isaacs, John T , Markowski, Mark C and Denmeade, Samuel R
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Testosterone is the canonical growth factor of prostate cancer but can paradoxically suppress its growth when present at supraphysiological levels. We have previously demonstrated that the cyclical administration of supraphysiological androgen (SPA), termed bipolar androgen therapy (BAT), can result in tumor regression and clinical benefit for pati...
Alternative Titles
Full title
Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC
Authors, Artists and Contributors
Author / Creator
Kumar, Rajendra
Sanin, David E
Thompson, Elizabeth A
Rosen, D Marc
Dalrymple, Susan L
Antony, Lizamma
Yang, Yuhan
Gomes-Alexandre, Carolina
Hicks, Jessica L
Jones, Tracy
Bowers, Kiara A
Eskra, Jillian N
Meyers, Jennifer
Gupta, Anuj
Skaist, Alyza
Yegnasubramanian, Srinivasan
Luo, Jun
Brennen, W Nathaniel
Kachhap, Sushant K
Antonarakis, Emmanuel S
De Marzo, Angelo M
Isaacs, John T
Markowski, Mark C
Denmeade, Samuel R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1190b8e3606d4217ab6c491c95462033
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1190b8e3606d4217ab6c491c95462033
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI162396
