Downregulation of the Glo1 Gene Is Associated with Reduced Adiposity and Ectopic Fat Accumulation in...
Downregulation of the Glo1 Gene Is Associated with Reduced Adiposity and Ectopic Fat Accumulation in Spontaneously Hypertensive Rats
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Methylglyoxal (MG), a potent precursor of advanced glycation end-products (AGE), is increased in metabolic disorders such as diabetes and obesity. MG and other dicarbonyl metabolites are detoxified by the glyoxalase system in which glyoxalase 1, coded by the Glo1 gene, serves as the rate-limiting enzyme. In this study, we analyzed the effects of Gl...
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Full title
Downregulation of the Glo1 Gene Is Associated with Reduced Adiposity and Ectopic Fat Accumulation in Spontaneously Hypertensive Rats
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TN_cdi_doaj_primary_oai_doaj_org_article_126578c8b040440fba45cd5f441464c1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_126578c8b040440fba45cd5f441464c1
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ISSN
2076-3921
E-ISSN
2076-3921
DOI
10.3390/antiox9121179
