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Hemodynamic Mechanisms Initiating Salt-Sensitive Hypertension in Rat Model of Primary Aldosteronism
Author / Creator:Pravenec, M ; Mlejnek, P ; Šimáková, M ; Šilhavý, J
Publisher:Praha: Institute of Physiology
Journal title:Physiological research, 2024-04, Vol.73 (Suppl 1), p.S365-S376
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Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats
Author / Creator:Liška, František ; Peterková, Renata ; Peterka, Miroslav ; Landa, Vladimír ; Zídek, Václav ; Mlejnek, Petr ; Šilhavý, Jan ; Šimáková, Miroslava ; Křen, Vladimír ; Starker, Colby G ; Voytas, Daniel F ; Izsvák, Zsuzsanna ; Pravenec, Michal
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-10, Vol.11 (10), p.e0164206-e0164206
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Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats
Author / Creator:Liška, František ; Peterková, Renata ; Peterka, Miroslav ; Landa, Vladimír ; Zídek, Václav ; Mlejnek, Petr ; Šilhavý, Jan ; Šimáková, Miroslava ; Křen, Vladimír ; Starker, Colby G ; Voytas, Daniel F ; Izsvák, Zsuzsanna ; Pravenec, Michal
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-01, Vol.15 (1), p.e0228139-e0228139
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Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturbances in transgenic spontaneously hypertensive rats
Author / Creator:Šilhavý, Jan ; Zídek, Václav ; Mlejnek, Petr ; Landa, Vladimír ; Šimáková, Miroslava ; Strnad, Hynek ; Oliyarnyk, Olena ; Škop, Vojtěch ; Kazdová, Ludmila ; Kurtz, Theodore ; Pravenec, Michal
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-07, Vol.9 (7), p.e101906
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Plzf as a candidate gene predisposing the spontaneously hypertensive rat to hypertension, left ventricular hypertrophy, and interstitial fibrosis
Author / Creator:Liška, František ; Mancini, Massimiliano ; Krupková, Michaela ; Chylíková, Blanka ; Křenová, Drahomíra ; Šeda, Ondřej ; Šilhavý, Jan ; Mlejnek, Petr ; Landa, Vladimír ; Zídek, Václav ; d' Amati, Giulia ; Pravenec, Michal ; Křen, Vladimír
Publisher:United States: Oxford University Press
Journal title:American journal of hypertension, 2014-01, Vol.27 (1), p.99-106
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Sodium Accumulation and Blood Capillary Rarefaction in the Skin Predispose Spontaneously Hypertensive Rats to Salt Sensitive Hypertension
Author / Creator:Šilhavý, Jan ; Mlejnek, Petr ; Šimáková, Miroslava ; Liška, František ; Kubovčiak, Jan ; Sticová, Eva ; Pravenec, Michal
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2022-02, Vol.10 (2), p.376
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Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic con...
Author / Creator:Trnovská, Jaroslava ; Šilhavý, Jan ; Kuda, Ondřej ; Landa, Vladimír ; Zídek, Václav ; Mlejnek, Petr ; Šimáková, Miroslava ; Strnad, Hynek ; Škop, Vojtěch ; Oliyarnyk, Olena ; Kazdová, Ludmila ; Haluzík, Martin ; Pravenec, Michal
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-06, Vol.12 (6), p.e0179063-e0179063
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Effects of Metformin on Tissue Oxidative and Dicarbonyl Stress in Transgenic Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein
Author / Creator:Malínská, Hana ; Oliyarnyk, Olena ; Škop, Vojtěch ; Šilhavý, Jan ; Landa, Vladimír ; Zídek, Václav ; Mlejnek, Petr ; Šimáková, Miroslava ; Strnad, Hynek ; Kazdová, Ludmila ; Pravenec, Michal
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-03, Vol.11 (3), p.e0150924-e0150924
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A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion
Author / Creator:Witte, Franziska ; Ruiz-Orera, Jorge ; Mattioli, Camilla Ciolli ; Blachut, Susanne ; Adami, Eleonora ; Schulz, Jana Felicitas ; Schneider-Lunitz, Valentin ; Hummel, Oliver ; Patone, Giannino ; Mücke, Michael Benedikt ; Šilhavý, Jan ; Heinig, Matthias ; Bottolo, Leonardo ; Sanchis, Daniel ; Vingron, Martin ; Chekulaeva, Marina ; Pravenec, Michal ; Hubner, Norbert ; van Heesch, Sebastiaan
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2021-06, Vol.22 (1), p.191-191, Article 191
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Folate Deficiency Is Associated With Oxidative Stress, Increased Blood Pressure, and Insulin Resistance in Spontaneously Hypertensive Rats
Author / Creator:Pravenec, Michal ; Kožich, Viktor ; Krijt, Jakub ; Sokolová, Jitka ; Zídek, Václav ; Landa, Vladimír ; Šimáková, Miroslava ; Mlejnek, Petr ; Šilhavý, Jan ; Oliyarnyk, Olena ; Kazdová, Ludmila ; Kurtz, Theodore W.
Publisher:US: Oxford University Press
Journal title:American journal of hypertension, 2013-01, Vol.26 (1), p.135-140
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CD36 regulates substrates utilisation in brown adipose tissue of spontaneously hypertensive rats: In vitro study
Author / Creator:Silhavy, Jan ; Mlejnek, Petr ; Šimáková, Miroslava ; Marková, Irena ; Malínská, Hana ; Hüttl, Martina ; Kazdová, Ludmila ; Kazantsev, Dmitry ; Mancini, Massimiliano ; Novotný, Jiří ; Pravenec, Michal
Publisher:United States: Public Library of Science
Journal title:PloS one, 2023-04, Vol.18 (4), p.e0283276-e0283276
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Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome
Author / Creator:Šilhavý, Jan ; Mlejnek, Petr ; Šimáková, Miroslava ; Malínská, Hana ; Marková, Irena ; Hüttl, Martina ; Miklánková, Denisa ; Kazdová, Ludmila ; Vrbacký, Marek ; Pecinová, Alena ; Mráček, Tomáš ; Pravenec, Michal
Publisher:Switzerland: MDPI AG
Journal title:Metabolites, 2023-01, Vol.13 (2), p.192
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Transgenic human C-reactive protein affects oxidative stress but not inflammation biomarkers in the aorta of spontaneously hypertensive rats
Author / Creator:Nemeckova, Ivana ; Eissazadeh, Samira ; Rathouska, Jana Urbankova ; Silhavy, Jan ; Malinska, Hana ; Pravenec, Michal ; Nachtigal, Petr
Publisher:England: BioMed Central Ltd
Journal title:BMC cardiovascular disorders, 2024-04, Vol.24 (1), p.211-9, Article 211
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Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein
Author / Creator:Malínská, Hana ; Hüttl, Martina ; Marková, Irena ; Miklánková, Denisa ; Hojná, Silvie ; Papoušek, František ; Šilhavý, Jan ; Mlejnek, Petr ; Zicha, Josef ; Hrdlička, Jaroslav ; Pravenec, Michal ; Vaněčková, Ivana
Publisher:Basel: MDPI AG
Journal title:Biomedicines, 2022-08, Vol.10 (9), p.2066
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Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility
Author / Creator:Mihola, Ondrej ; Landa, Vladimir ; Pratto, Florencia ; Brick, Kevin ; Kobets, Tatyana ; Kusari, Fitore ; Gasic, Srdjan ; Smagulova, Fatima ; Grey, Corinne ; Flachs, Petr ; Gergelits, Vaclav ; Tresnak, Karel ; Silhavy, Jan ; Mlejnek, Petr ; Camerini-Otero, R Daniel ; Pravenec, Michal ; Petukhova, Galina V ; Trachtulec, Zdenek
Publisher:England: BioMed Central
Journal title:BMC biology, 2021-04, Vol.19 (1), p.86-86, Article 86
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Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome
Author / Creator:Pecina, Petr ; Čunátová, Kristýna ; Kaplanová, Vilma ; Puertas-Frias, Guillermo ; Šilhavý, Jan ; Tauchmannová, Kateřina ; Vrbacký, Marek ; Čajka, Tomáš ; Gahura, Ondřej ; Hlaváčková, Markéta ; Stránecký, Viktor ; Kmoch, Stanislav ; Pravenec, Michal ; Houštěk, Josef ; Mráček, Tomáš ; Pecinová, Alena
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2024-09, Vol.7 (1), p.1116-17, Article 1116
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Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose
Author / Creator:Senko, Anna N ; Overall, Rupert W ; Silhavy, Jan ; Mlejnek, Petr ; Malínská, Hana ; Hüttl, Martina ; Marková, Irena ; Fabel, Klaus S ; Lu, Lu ; Stuchlik, Ales ; Williams, Robert W ; Pravenec, Michal ; Kempermann, Gerd
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2022-04, Vol.18 (4), p.e1009638
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Hepatic Transcriptome Profiling Reveals Lack of Acsm3 Expression in Polydactylous Rats with High-Fat Diet-Induced Hypertriglyceridemia and Visceral Fat Accumulation
Author / Creator:Junková, Kristýna ; Mirchi, Lukáš F ; Chylíková, Blanka ; Janků, Michaela ; Šilhavý, Jan ; Hüttl, Martina ; Marková, Irena ; Miklánková, Denisa ; Včelák, Josef ; Malínská, Hana ; Pravenec, Michal ; Šeda, Ondřej ; Liška, František
Publisher:Switzerland: MDPI AG
Journal title:Nutrients, 2021-04, Vol.13 (5), p.1462
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Nestin expression in the myocardium of normotensive and spontaneously hypertensive rats during aging
Author / Creator:Cizkova, Dana ; Zurmanova, Jitka M. ; Gerykova, Lucie ; Elsnicova, Barbara ; Galatik, Frantisek ; Silhavy, Jan ; Pravenec, Michal ; Mokry, Jaroslav
Publisher:Les Ulis: EDP Sciences
Journal title:BIO web of conferences, 2024, Vol.129, p.17028
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High Cysteine Diet Reduces Insulin Resistance in SHR-CRP Rats
Author / Creator:KRIJT, J ; SOKOLOVÁ, J ; ŠILHAVÝ, J ; MLEJNEK, P ; KUBOVČIAK, J ; LIŠKA, F ; MALÍNSKÁ, H ; HÜTTL, M ; MARKOVÁ, I ; KŘÍŽKOVÁ, M ; STIPANUK, M ; KŘÍŽEK, T ; DITROI, T ; NAGY, P ; KOŽICH, V ; PRAVENEC, M
Publisher:Praha: Institute of Physiology
Journal title:Physiological research, 2021-11, Vol.70 (5), p.687-700
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Hemodynamic Mechanisms Initiating Salt-Sensitive Hypertension in Rat Model of Primary Aldosteronism

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Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats

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Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats

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Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturbances in transgenic spontaneously hypertensive rats

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Plzf as a candidate gene predisposing the spontaneously hypertensive rat to hypertension, left ventricular hypertrophy, and interstitial fibrosis

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Sodium Accumulation and Blood Capillary Rarefaction in the Skin Predispose Spontaneously Hypertensive Rats to Salt Sensitive Hypertension

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Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic con...

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Effects of Metformin on Tissue Oxidative and Dicarbonyl Stress in Transgenic Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein

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A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion

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Folate Deficiency Is Associated With Oxidative Stress, Increased Blood Pressure, and Insulin Resistance in Spontaneously Hypertensive Rats

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CD36 regulates substrates utilisation in brown adipose tissue of spontaneously hypertensive rats: In vitro study

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Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome

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Transgenic human C-reactive protein affects oxidative stress but not inflammation biomarkers in the aorta of spontaneously hypertensive rats

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Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein

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Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility

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Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome

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Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose

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Hepatic Transcriptome Profiling Reveals Lack of Acsm3 Expression in Polydactylous Rats with High-Fat Diet-Induced Hypertriglyceridemia and Visceral Fat Accumulation

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Nestin expression in the myocardium of normotensive and spontaneously hypertensive rats during aging

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High Cysteine Diet Reduces Insulin Resistance in SHR-CRP Rats

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