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Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calci...

Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calci...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_126b49e946bc446587919a74f95203cf

Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels

About this item

Full title

Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-09, Vol.14 (1), p.5500-20, Article 5500

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Astrocytes contribute to brain inflammation in neurological disorders but the molecular mechanisms controlling astrocyte reactivity and their relationship to neuroinflammatory endpoints are complex and poorly understood. In this study, we assessed the role of the calcium channel, Orai1, for astrocyte reactivity and inflammation-evoked depression be...

Alternative Titles

Full title

Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_126b49e946bc446587919a74f95203cf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_126b49e946bc446587919a74f95203cf

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-40968-6

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