Memory and relatedness of transcriptional activity in mammalian cell lineages
Memory and relatedness of transcriptional activity in mammalian cell lineages
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Phenotypically identical mammalian cells often display considerable variability in transcript levels of individual genes. How transcriptional activity propagates in cell lineages, and how this varies across genes is poorly understood. Here we combine live-cell imaging of short-lived transcriptional reporters in mouse embryonic stem cells with mathe...
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Memory and relatedness of transcriptional activity in mammalian cell lineages
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TN_cdi_doaj_primary_oai_doaj_org_article_129c79e594114d3db8f9415be1533700
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_129c79e594114d3db8f9415be1533700
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09189-8
