PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK
PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The signaling lipid phosphatidylinositol-4,5-bisphosphate (PIP2) regulates many ion channels. It inhibits eukaryotic cyclic nucleotide-gated (CNG) channels while activating their relatives, the hyperpolarization-activated and cyclic nucleotide-modulated (HCN) channels. The prokaryotic SthK channel from
Spirochaeta thermophila
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Full title
PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK
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TN_cdi_doaj_primary_oai_doaj_org_article_12e792ed604a43c2a3ec56fd0d939e1f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_12e792ed604a43c2a3ec56fd0d939e1f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52469-1
