Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct ma...
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners
About this item
Full title
Author / Creator
Li, Xingyan , Zhang, Mengmeng , Huang, Xinyue , Liang, Wei , Li, Ganquan , Lu, Xiaojuan , Li, Yanxia , Pan, Heling , Shi, Linyu , Zhu, Hong , Qian, Lihui , Shan, Bing and Yuan, Junying
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
RIPK1 is a death-domain (DD) containing kinase involved in regulating apoptosis, necroptosis and inflammation. RIPK1 activation is known to be regulated by its DD-mediated interaction and ubiquitination, though underlying mechanisms remain incompletely understood. Here we show that K627 in human RIPK1-DD and its equivalent K612 in murine RIPK1-DD i...
Alternative Titles
Full title
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_13104a8bcb9e4fa4a4030c31c509ba7c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13104a8bcb9e4fa4a4030c31c509ba7c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-19935-y
