Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obe...
Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS
About this item
Full title
Author / Creator
Pan, David Z. , Garske, Kristina M. , Alvarez, Marcus , Bhagat, Yash V. , Boocock, James , Nikkola, Elina , Miao, Zong , Raulerson, Chelsea K. , Cantor, Rita M. , Civelek, Mete , Glastonbury, Craig A. , Small, Kerrin S. , Boehnke, Michael , Lusis, Aldons J. , Sinsheimer, Janet S. , Mohlke, Karen L. , Laakso, Markku , Pajukanta, Päivi and Ko, Arthur
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Increased adiposity is a hallmark of obesity and overweight, which affect 2.2 billion people world-wide. Understanding the genetic and molecular mechanisms that underlie obesity-related phenotypes can help to improve treatment options and drug development. Here we perform promoter Capture Hi–C in human adipocytes to investigate interactions between...
Alternative Titles
Full title
Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS
Authors, Artists and Contributors
Author / Creator
Garske, Kristina M.
Alvarez, Marcus
Bhagat, Yash V.
Boocock, James
Nikkola, Elina
Miao, Zong
Raulerson, Chelsea K.
Cantor, Rita M.
Civelek, Mete
Glastonbury, Craig A.
Small, Kerrin S.
Boehnke, Michael
Lusis, Aldons J.
Sinsheimer, Janet S.
Mohlke, Karen L.
Laakso, Markku
Pajukanta, Päivi
Ko, Arthur
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_133629e0a6304f2f8d3499574a04d269
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_133629e0a6304f2f8d3499574a04d269
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03554-9
