Functional and genetic determinants of mutation rate variability in regulatory elements of cancer ge...
Functional and genetic determinants of mutation rate variability in regulatory elements of cancer genomes
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Cancer genomes are shaped by mutational processes with complex spatial variation at multiple scales. Entire classes of regulatory elements are affected by local variations in mutation frequency. However, the underlying mechanisms with functional and genetic determinants remain poorly understood.
We characterise the mutational landscape of 1.3 mi...
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Full title
Functional and genetic determinants of mutation rate variability in regulatory elements of cancer genomes
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TN_cdi_doaj_primary_oai_doaj_org_article_13eeb157c3ea471ca6f82c2ee6b6e5f2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13eeb157c3ea471ca6f82c2ee6b6e5f2
Other Identifiers
ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-021-02318-x
