Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1G93A mice and modula...
Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1G93A mice and modulates expression of prognosis biomarkers of the disease
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive muscle weakness, paralysis and death. There is no effective treatment for ALS and stem cell therapy has arisen as a potential therapeutic approach. Methods SOD1 mutant mice were used to study the potential neurotrophic effect of bone marrow c...
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Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1G93A mice and modulates expression of prognosis biomarkers of the disease
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TN_cdi_doaj_primary_oai_doaj_org_article_14b3ec59f88a40beb9ef009ee12b7056
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_14b3ec59f88a40beb9ef009ee12b7056
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1757-6512
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1757-6512
DOI
10.1186/s13287-018-0843-z