β7 integrins contribute to intestinal tumor growth in mice
β7 integrins contribute to intestinal tumor growth in mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The gut homing receptor integrin α4β7 is essential for the migration of pro-inflammatory T cells into the gut mucosa. Since intestinal neoplasia has been associated with chronic inflammation, we investigated whether interfering with gut-homing affects intestinal tumorigenesis. Using chemically induced and spontaneous intestinal tumor models we show...
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β7 integrins contribute to intestinal tumor growth in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_1506e9fe7ed843ea8a74eb9c5e6a9d81
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1506e9fe7ed843ea8a74eb9c5e6a9d81
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0204181