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β7 integrins contribute to intestinal tumor growth in mice

β7 integrins contribute to intestinal tumor growth in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1506e9fe7ed843ea8a74eb9c5e6a9d81

β7 integrins contribute to intestinal tumor growth in mice

About this item

Full title

β7 integrins contribute to intestinal tumor growth in mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018, Vol.13 (9), p.e0204181-e0204181

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The gut homing receptor integrin α4β7 is essential for the migration of pro-inflammatory T cells into the gut mucosa. Since intestinal neoplasia has been associated with chronic inflammation, we investigated whether interfering with gut-homing affects intestinal tumorigenesis. Using chemically induced and spontaneous intestinal tumor models we show...

Alternative Titles

Full title

β7 integrins contribute to intestinal tumor growth in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1506e9fe7ed843ea8a74eb9c5e6a9d81

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1506e9fe7ed843ea8a74eb9c5e6a9d81

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0204181

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