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Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_154add9708db44f79ef13ed15572133f

Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

About this item

Full title

Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

Publisher

Switzerland: MDPI AG

Journal title

Antibodies (Basel), 2018-07, Vol.7 (3), p.25

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Aβ is the toxic amyloid polypeptide responsible for Alzheimer's disease (AD). Prevention and elimination of the Aβ misfolded aggregates are the promising therapeutic strategies for the AD treatments. Gammabody, the Aβ-Specific Single-domain (VH) antibody, recognizes Aβ aggregates with high affinity and specificity and reduces their toxicities. Empl...

Alternative Titles

Full title

Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_154add9708db44f79ef13ed15572133f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_154add9708db44f79ef13ed15572133f

Other Identifiers

ISSN

2073-4468

E-ISSN

2073-4468

DOI

10.3390/antib7030025

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