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Remyelination protects neurons from DLK-mediated neurodegeneration

Remyelination protects neurons from DLK-mediated neurodegeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_157dbf6e704c453ab56f2275e3086749

Remyelination protects neurons from DLK-mediated neurodegeneration

About this item

Full title

Remyelination protects neurons from DLK-mediated neurodegeneration

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-10, Vol.15 (1), p.9148-19, Article 9148

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Chronic demyelination and oligodendrocyte loss deprive neurons of crucial support. It is the degeneration of neurons and their connections that drives progressive disability in demyelinating disease. However, whether chronic demyelination triggers neurodegeneration and how it may do so remain unclear. We characterize two genetic mouse models of ind...

Alternative Titles

Full title

Remyelination protects neurons from DLK-mediated neurodegeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_157dbf6e704c453ab56f2275e3086749

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_157dbf6e704c453ab56f2275e3086749

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-53429-5

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