Tumour-originated exosomal miR-155 triggers cancer-associated cachexia to promote tumour progression
Tumour-originated exosomal miR-155 triggers cancer-associated cachexia to promote tumour progression
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Author / Creator
Wu, Qi , Sun, Si , Li, Zhiyu , Yang, Qian , Li, Bei , Zhu, Shan , Wang, Lijun , Wu, Juan , Yuan, Jingping , Yang, Changhua , Li, Juanjuan and Sun, Shengrong
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Emerging evidence supports the pivotal roles of cancer-associated cachexia in breast cancer progression. However, the mediators and mechanisms that mediate cancer-induced cachexia remain unclear. Here, we show that breast cancer-derived exosomes alter adipocytes and muscle cells in terms of increased catabolism characterized by the release of metab...
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Full title
Tumour-originated exosomal miR-155 triggers cancer-associated cachexia to promote tumour progression
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_15d6285a2e1d420aaefa5021d9f52704
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15d6285a2e1d420aaefa5021d9f52704
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-018-0899-5