Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in...
Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers
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England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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Substrate-binding proteins (SBPs) are associated with ATP-binding cassette importers and switch from an open to a closed conformation upon substrate binding, providing specificity for transport. We investigated the effect of substrates on the conformational dynamics of six SBPs and the impact on transport. Using single-molecule FRET, we reveal an u...
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Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers
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TN_cdi_doaj_primary_oai_doaj_org_article_15f0005b2cc34729a8f4bc4b49571c6b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15f0005b2cc34729a8f4bc4b49571c6b
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.44652
