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Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chro...

Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_162243061cbc414bb1ca08196034caa5

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

HBsAg immune-escape mutations can favor HBV-transmission also in vaccinated individuals, promote immunosuppression-driven HBV-reactivation, and increase fitness of drug-resistant strains. Stop-codons can enhance HBV oncogenic-properties. Furthermore, as a consequence of the overlapping structure of HBV genome, some immune-escape mutations or stop-c...

Alternative Titles

Full title

Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chronic HBV infection exposed to anti-HBV drugs in Europe

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_162243061cbc414bb1ca08196034caa5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_162243061cbc414bb1ca08196034caa5

Other Identifiers

ISSN

1471-2334

E-ISSN

1471-2334

DOI

10.1186/s12879-018-3161-2

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