Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of t...
Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis
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Author / Creator
Ren, Yifan , Liu, Wuming , zhang, Lin , Zhang, Jia , Bi, Jianbin , Wang, Tao , Wang, Mengzhou , Du, Zhaoqing , Wang, Yawen , zhang, Lin , Wu, Zheng , Lv, Yi , Meng, Lingzhong and Wu, Rongqian
Publisher
United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Contents
Acute pancreatitis (AP) remains a significant clinical challenge. Mitochondrial dysfunction contributes significantly to the pathogenesis of AP. Milk fat globule EGF factor 8 (MFG‐E8) is an opsonizing protein, which has many biological functions via binding to αvβ3/5 integrins. Ligand‐dependent integrin‐FAK activation of STAT3 was reported to be of...
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Full title
Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis
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TN_cdi_doaj_primary_oai_doaj_org_article_1637a0164d39410fbd88c51023b055e6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1637a0164d39410fbd88c51023b055e6
Other Identifiers
ISSN
2001-1326
E-ISSN
2001-1326
DOI
10.1002/ctm2.295