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Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of t...

Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1637a0164d39410fbd88c51023b055e6

Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis

About this item

Full title

Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis

Publisher

United States: John Wiley & Sons, Inc

Journal title

Clinical and Translational Medicine, 2021-02, Vol.11 (2), p.e295-n/a

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Acute pancreatitis (AP) remains a significant clinical challenge. Mitochondrial dysfunction contributes significantly to the pathogenesis of AP. Milk fat globule EGF factor 8 (MFG‐E8) is an opsonizing protein, which has many biological functions via binding to αvβ3/5 integrins. Ligand‐dependent integrin‐FAK activation of STAT3 was reported to be of...

Alternative Titles

Full title

Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1637a0164d39410fbd88c51023b055e6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1637a0164d39410fbd88c51023b055e6

Other Identifiers

ISSN

2001-1326

E-ISSN

2001-1326

DOI

10.1002/ctm2.295

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