Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by s...
Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing
About this item
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Author / Creator
Bartoschek, Michael , Oskolkov, Nikolay , Bocci, Matteo , Lövrot, John , Larsson, Christer , Sommarin, Mikael , Madsen, Chris D. , Lindgren, David , Pekar, Gyula , Karlsson, Göran , Ringnér, Markus , Bergh, Jonas , Björklund, Åsa , Pietras, Kristian , Faculty of Medicine , Experimental oncology , Medicinska fakulteten , Division of Molecular Hematology (DMH) , Strategiska forskningsområden (SFO) , Njurcancergruppen , StemTherapy: National Initiative on Stem Cells for Regenerative Therapy , Department of Laboratory Medicine , Division of Translational Cancer Research , Experimentell onkologi , Strategic research areas (SRA) , Lunds universitet , Tumörcellsbiologi , Avdelningen för molekylär hematologi , Profilområden och andra starka forskningsmiljöer , Lund University , Avdelningen för translationell cancerforskning , Institutionen för laboratoriemedicin , Tumor Cell Biology , Profile areas and other strong research environments , Stem Cells and Leukemia and Kidney cancer research group
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cancer-associated fibroblasts (CAFs) are a major constituent of the tumor microenvironment, although their origin and roles in shaping disease initiation, progression and treatment response remain unclear due to significant heterogeneity. Here, following a negative selection strategy combined with single-cell RNA sequencing of 768 transcriptomes of...
Alternative Titles
Full title
Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing
Authors, Artists and Contributors
Author / Creator
Oskolkov, Nikolay
Bocci, Matteo
Lövrot, John
Larsson, Christer
Sommarin, Mikael
Madsen, Chris D.
Lindgren, David
Pekar, Gyula
Karlsson, Göran
Ringnér, Markus
Bergh, Jonas
Björklund, Åsa
Pietras, Kristian
Faculty of Medicine
Experimental oncology
Medicinska fakulteten
Division of Molecular Hematology (DMH)
Strategiska forskningsområden (SFO)
Njurcancergruppen
StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
Department of Laboratory Medicine
Division of Translational Cancer Research
Experimentell onkologi
Strategic research areas (SRA)
Lunds universitet
Tumörcellsbiologi
Avdelningen för molekylär hematologi
Profilområden och andra starka forskningsmiljöer
Lund University
Avdelningen för translationell cancerforskning
Institutionen för laboratoriemedicin
Tumor Cell Biology
Profile areas and other strong research environments
Stem Cells and Leukemia
Kidney cancer research group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1659aa31381d4c7a92e2ff7e1c638daf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1659aa31381d4c7a92e2ff7e1c638daf
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07582-3
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