18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes
18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes
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Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States) , Tsai, Richard M. , Bejanin, Alexandre , Lesman-Segev, Orit , LaJoie, Renaud , Visani, Adrienne , Bourakova, Viktoriya , O’Neil, James P. , Janabi, Mustafa , Baker, Suzanne , Lee, Suzee E. , Perry, David C. , Bajorek, Lynn , Karydas, Anna , Spina, Salvatore , Grinberg, Lea T. , Seeley, William W. , Ramos, Eliana M. , Coppola, Giovanni , Gorno-Tempini, Maria Luisa , Miller, Bruce L. , Rosen, Howard J. , Jagust, William , Boxer, Adam L. and Rabinovici, Gil D.
Publisher
London: BioMed Central Ltd
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English
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Publisher
London: BioMed Central Ltd
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Contents
Background The tau positron emission tomography (PET) ligand .sup.18F-flortaucipir binds to paired helical filaments of tau in aging and Alzheimer's disease (AD), but its utility in detecting tau aggregates in frontotemporal dementia (FTD) is uncertain. Methods We performed .sup.18F-flortaucipir imaging in patients with the FTD syndromes (n = 45):...
Alternative Titles
Full title
18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes
Authors, Artists and Contributors
Author / Creator
Tsai, Richard M.
Bejanin, Alexandre
Lesman-Segev, Orit
LaJoie, Renaud
Visani, Adrienne
Bourakova, Viktoriya
O’Neil, James P.
Janabi, Mustafa
Baker, Suzanne
Lee, Suzee E.
Perry, David C.
Bajorek, Lynn
Karydas, Anna
Spina, Salvatore
Grinberg, Lea T.
Seeley, William W.
Ramos, Eliana M.
Coppola, Giovanni
Gorno-Tempini, Maria Luisa
Miller, Bruce L.
Rosen, Howard J.
Jagust, William
Boxer, Adam L.
Rabinovici, Gil D.
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Primary Identifiers
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TN_cdi_doaj_primary_oai_doaj_org_article_1733aae59d224cd5a72a1f4f4fc79342
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1733aae59d224cd5a72a1f4f4fc79342
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ISSN
1758-9193
E-ISSN
1758-9193
DOI
10.1186/s13195-019-0470-7