Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF
Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF
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Xu, Chuan , Tang, Dongdong , Shao, Zhongmei , Geng, Hao , Gao, Yang , Li, Kuokuo , Tan, Qing , Wang, Guanxiong , Wang, Chao , Wu, Huan , Li, Guanjian , Lv, Mingrong , He, Xiaojin and Cao, Yunxia
Publisher
England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Contents
Multiple morphological abnormalities of the sperm flagella (MMAF) is a subtype of severe asthenoteratozoospermia with poorly understood genetic etiology. SPAG6 is a core axonemal component that plays a critical role in the formation of cilia and sperm flagella. Previous studies have reported that mutations in SPAG6 cause primary ciliary dyskinesia...
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Full title
Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF
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TN_cdi_doaj_primary_oai_doaj_org_article_1759dcd5eafb472a9e0f1220896929f4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1759dcd5eafb472a9e0f1220896929f4
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ISSN
1477-7827
E-ISSN
1477-7827
DOI
10.1186/s12958-022-00916-3
