Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excl...
Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Chemoimmunotherapy has recently failed to demonstrate significant clinical benefit in advanced bladder cancer patients; and the mechanism(s) underlying such suboptimal response remain elusive. To date, most studies have focused on tumor-intrinsic properties that render them “immune-excluded”. Here, we explore an alternative, drug-induced mechanism...
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Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors
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TN_cdi_doaj_primary_oai_doaj_org_article_176073b4ee2c4398bc3a707bca588745
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_176073b4ee2c4398bc3a707bca588745
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29026-9
