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ArticlesPeer ReviewedFull Text
Y chromosome loss in cancer drives growth by evasion of adaptive immunity
Author / Creator:Abdel-Hafiz, Hany A. ; Schafer, Johanna M. ; Chen, Xingyu ; Xiao, Tong ; Gauntner, Timothy D. ; Li, Zihai ; Theodorescu, Dan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-07, Vol.619 (7970), p.624-631
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ArticlesPeer ReviewedFull Text
Learning therapeutic lessons from metastasis suppressor proteins
Author / Creator:Smith, Steven Christopher ; Theodorescu, Dan
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2009-04, Vol.9 (4), p.253-264
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ArticlesPeer ReviewedFull Text
Metastasis: a therapeutic target for cancer
Author / Creator:Steeg, Patricia S ; Theodorescu, Dan
Publisher:London: Nature Publishing Group UK
Journal title:Nature clinical practice. Oncology, 2008-04, Vol.5 (4), p.206-219
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ArticlesPeer ReviewedFull Text
An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer
Author / Creator:Gouin, Kenneth H. ; Ing, Nathan ; Plummer, Jasmine T. ; Rosser, Charles J. ; Ben Cheikh, Bassem ; Oh, Catherine ; Chen, Stephanie S. ; Chan, Keith Syson ; Furuya, Hideki ; Tourtellotte, Warren G. ; Knott, Simon R. V. ; Theodorescu, Dan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-08, Vol.12 (1), p.4906-4906, Article 4906
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ArticlesPeer ReviewedFull Text
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
Author / Creator:Killela, Patrick J. ; Reitman, Zachary J. ; Jiao, Yuchen ; Bettegowda, Chetan ; Agrawal, Nishant ; Diaz, Luis A. ; Friedman, Allan H. ; Friedman, Henry ; Gallia, Gary L. ; Giovanella, Beppino C. ; Grollman, Arthur P. ; He, Tong-Chuan ; He, Yiping ; Hruban, Ralph H. ; Jallo, George I. ; Mandahl, Nils ; Meeker, Alan K. ; Mertens, Fredrik ; Netto, George J. ; Rasheed, B. Ahmed ; Riggins, Gregory J. ; Rosenquist, Thomas A. ; Schiffman, Mark ; Shih, Ie-Ming ; Theodorescu, Dan ; Torbenson, Michael S. ; Velculescu, Victor E. ; Wang, Tian-Li ; Wentzensen, Nicolas ; Wood, Laura D. ; Zhang, Ming ; McLendon, Roger E. ; Bigner, Darell D. ; Kinzler, Kenneth W. ; Vogelstein, Bert ; Papadopoulos, Nickolas ; Yan, Hai
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.6021-6026
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ArticlesPeer ReviewedFull Text
The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer
Author / Creator:Guin, Sunny ; Theodorescu, Dan
Publisher:London: Nature Publishing Group UK
Journal title:Acta pharmacologica Sinica, 2015-03, Vol.36 (3), p.291-297
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The RAS-RAL axis in cancer： evidence for mutationspecific selectivity in non-small cell lung cancer
Author / Creator:Sunny GUIN Dan THEODORESCU
Journal title:中国药理学报：英文版, 2015 (3), p.291-297
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ArticlesPeer ReviewedFull Text
Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer
Author / Creator:Said, Neveen ; Smith, Steven ; Sanchez-Carbayo, Marta ; Theodorescu, Dan
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-01, Vol.121 (1), p.132-147
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ArticlesPeer ReviewedFull Text
Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors
Author / Creator:Nikolos, Fotis ; Hayashi, Kazukuni ; Hoi, Xen Ping ; Alonzo, Mark Ellie ; Mo, Qianxing ; Kasabyan, Armine ; Furuya, Hideki ; Trepel, Jane ; Di Vizio, Dolores ; Guarnerio, Jlenia ; Theodorescu, Dan ; Rosser, Charles ; Apolo, Andrea ; Galsky, Matthew ; Chan, Keith Syson
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-03, Vol.13 (1), p.1487-16, Article 1487
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ArticlesPeer ReviewedFull Text
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
Author / Creator:Gui, Yaoting ; Guo, Guangwu ; Huang, Yi ; Hu, Xueda ; Tang, Aifa ; Gao, Shengjie ; Wu, Renhua ; Chen, Chao ; Li, Xianxin ; Zhou, Liang ; He, Minghui ; Li, Zesong ; Sun, Xiaojuan ; Jia, Wenlong ; Chen, Jinnong ; Yang, Shangming ; Zhou, Fangjian ; Zhao, Xiaokun ; Wan, Shengqing ; Ye, Rui ; Liang, Chaozhao ; Liu, Zhisheng ; Huang, Peide ; Liu, Chunxiao ; Jiang, Hui ; Wang, Yong ; Zheng, Hancheng ; Sun, Liang ; Liu, Xingwang ; Jiang, Zhimao ; Feng, Dafei ; Chen, Jing ; Wu, Song ; Zou, Jing ; Zhang, Zhongfu ; Yang, Ruilin ; Zhao, Jun ; Xu, Congjie ; Yin, Weihua ; Guan, Zhichen ; Ye, Jiongxian ; Zhang, Hong ; Li, Jingxiang ; Kristiansen, Karsten ; Nickerson, Michael L ; Theodorescu, Dan ; Li, Yingrui ; Zhang, Xiuqing ; Li, Songgang ; Wang, Jian ; Yang, Huanming ; Wang, Jun ; Cai, Zhiming
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2011-09, Vol.43 (9), p.875-878
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ArticlesPeer ReviewedFull Text
Metastatic cells are preferentially vulnerable to lysosomal inhibition
Author / Creator:Morgan, Michael J. ; Fitzwalter, Brent E. ; Owens, Charles R. ; Powers, Rani K. ; Sottnik, Joseph L. ; Gamez, Graciela ; Costello, James C. ; Theodorescu, Dan ; Thorburn, Andrew
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (36), p.E8479-E8488
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Newsletter articlesFull Text
Theodorescu Dan, Wempe Michael Fitzpatrick, Ross David, Meroueh Samy, Schwartz Martin A and Reigan Phillip Submit United States Patent Application for Anti-Cancer Compounds Targeting Ral Gtpases and M...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2016
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ArticlesPeer ReviewedFull Text
Targetable Pathways in Advanced Bladder Cancer: FGFR Signaling
Author / Creator:Xiao, Jin-Fen ; Caliri, Andrew W. ; Duex, Jason E. ; Theodorescu, Dan
Publisher:Basel: MDPI AG
Journal title:Cancers, 2021-09, Vol.13 (19), p.4891
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ArticlesPeer ReviewedFull Text
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy
Author / Creator:Tu, Megan M. ; Abdel-Hafiz, Hany A. ; Jones, Robert T. ; Jean, Annie ; Hoff, Katelyn J. ; Duex, Jason E. ; Chauca-Diaz, Ana ; Costello, James C. ; Dancik, Garrett M. ; Tamburini, Beth A. Jirón ; Czerniak, Bogdan ; Kaye, Jonathan ; Theodorescu, Dan
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2020-11, Vol.3 (1), p.720-720, Article 720
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ArticlesPeer ReviewedFull Text
Loss of SPARC in bladder cancer enhances carcinogenesis and progression
Author / Creator:Said, Neveen ; Frierson, Henry F. ; Sanchez-Carbayo, Marta ; Brekken, Rolf A. ; Theodorescu, Dan
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-02, Vol.123 (2), p.751-751
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ArticlesPeer ReviewedFull Text
Robust Prognostic Gene Expression Signatures in Bladder Cancer and Lung Adenocarcinoma Depend on Cell Cycle Related Genes
Author / Creator:Dancik, Garrett M. ; Theodorescu, Dan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-01, Vol.9 (1), p.e85249-e85249
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ArticlesPeer ReviewedFull Text
Genes driving three-dimensional growth of immortalized cells and cancer
Author / Creator:Basu, Mukta ; Xiao, Jin-Fen ; Kailasam Mani, Saravana Kumar ; Qu, Fangyuan ; Lin, Yongqi ; Duex, Jason ; Ye, Huihui ; Neang, Vanessa ; Theodorescu, Dan
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2025-06, Vol.16 (1), p.442-11
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ArticlesPeer ReviewedFull Text
RalA controls glucose homeostasis by regulating glucose uptake in brown fat
Author / Creator:Skorobogatko, Yuliya ; Dragan, Morgan ; Cordon, Claudia ; Reilly, Shannon M. ; Hung, Chao-Wei ; Xia, Wenmin ; Zhao, Peng ; Wallace, Martina ; Lackey, Denise E. ; Chen, Xiao-Wei ; 陈晓伟 ; Osborn, Olivia ; Bogner-Strauss, Juliane G. ; Theodorescu, Dan ; Metallo, Christian M. ; Olefsky, Jerrold M. ; Saltiel, Alan R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.7819-7824
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ArticlesPeer ReviewedFull Text
strategy for predicting the chemosensitivity of human cancers and its application to drug discovery
Author / Creator:Lee, Jae K ; Havaleshko, Dmytro M ; Cho, HyungJun ; Weinstein, John N ; Kaldjian, Eric P ; Karpovich, John ; Grimshaw, Andrew ; Theodorescu, Dan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (32), p.13086-13091
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ArticlesPeer ReviewedFull Text
A whole-genome RNAi screen uncovers a novel role for human potassium channels in cell killing by the parasite Entamoeba histolytica
Author / Creator:Marie, Chelsea ; Verkerke, Hans P. ; Theodorescu, Dan ; Petri, William A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-09, Vol.5 (1), p.13613-13613, Article 13613
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Showing 1 to 20 of 129 results

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Y chromosome loss in cancer drives growth by evasion of adaptive immunity

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Learning therapeutic lessons from metastasis suppressor proteins

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Metastasis: a therapeutic target for cancer

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An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer

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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

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The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer

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The RAS-RAL axis in cancer： evidence for mutationspecific selectivity in non-small cell lung cancer

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Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer

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Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors

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Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

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Metastatic cells are preferentially vulnerable to lysosomal inhibition

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Theodorescu Dan, Wempe Michael Fitzpatrick, Ross David, Meroueh Samy, Schwartz Martin A and Reigan Phillip Submit United States Patent Application for Anti-Cancer Compounds Targeting Ral Gtpases and M...

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Targetable Pathways in Advanced Bladder Cancer: FGFR Signaling

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Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy

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Loss of SPARC in bladder cancer enhances carcinogenesis and progression

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Robust Prognostic Gene Expression Signatures in Bladder Cancer and Lung Adenocarcinoma Depend on Cell Cycle Related Genes

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Genes driving three-dimensional growth of immortalized cells and cancer

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RalA controls glucose homeostasis by regulating glucose uptake in brown fat

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strategy for predicting the chemosensitivity of human cancers and its application to drug discovery

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A whole-genome RNAi screen uncovers a novel role for human potassium channels in cell killing by the parasite Entamoeba histolytica

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