Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glyc...
Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glycolysis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Human chromosome 9p21.3 is susceptible to inactivation in cell immortalization and diseases, such as cancer, coronary artery disease and type-2 diabetes. Although this locus encodes three cyclin-dependent kinase (CDK) inhibitors (p15
INK4B
, p14
ARF
and p16
INK4A
), our understanding of their functions and modes of action is limit...
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Full title
Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glycolysis
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TN_cdi_doaj_primary_oai_doaj_org_article_1794a8df136e4fa498e705b2124da7e9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1794a8df136e4fa498e705b2124da7e9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22327-5
