Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of...
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Metastatic colonization relies on interactions between disseminated cancer cells and the microenvironment in secondary organs. Here, we show that disseminated breast cancer cells evoke phenotypic changes in lung fibroblasts, forming a supportive metastatic niche. Colonization of the lungs confers an inflammatory phenotype in metastasis-associated f...
Alternative Titles
Full title
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_17acb7c31f7941f0959b5034c6bfd4bc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17acb7c31f7941f0959b5034c6bfd4bc
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15188-x