Single‐Nucleus RNA Sequencing and Spatial Transcriptomics Reveal the Immunological Microenvironment...
Single‐Nucleus RNA Sequencing and Spatial Transcriptomics Reveal the Immunological Microenvironment of Cervical Squamous Cell Carcinoma
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Author / Creator
Ou, Zhihua , Lin, Shitong , Qiu, Jiaying , Ding, Wencheng , Ren, Peidi , Chen, Dongsheng , Wang, Jiaxuan , Tong, Yihan , Wu, Di , Chen, Ao , Deng, Yuan , Cheng, Mengnan , Peng, Ting , Lu, Haorong , Yang, Huanming , Wang, Jian , Jin, Xin , Ma, Ding , Xu, Xun , Wang, Yanzhou , Li, Junhua and Wu, Peng
Publisher
Germany: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
Germany: John Wiley & Sons, Inc
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Contents
The effective treatment of advanced cervical cancer remains challenging. Herein, single‐nucleus RNA sequencing (snRNA‐seq) and SpaTial enhanced resolution omics‐sequencing (Stereo‐seq) are used to investigate the immunological microenvironment of cervical squamous cell carcinoma (CSCC). The expression levels of most immune suppressive genes in the...
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Full title
Single‐Nucleus RNA Sequencing and Spatial Transcriptomics Reveal the Immunological Microenvironment of Cervical Squamous Cell Carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_17fadd43f70142cf85c07bc9cdf5c6ea
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17fadd43f70142cf85c07bc9cdf5c6ea
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202203040
