HOPS-Dependent Endosomal Escape Demands Protein Unfolding
HOPS-Dependent Endosomal Escape Demands Protein Unfolding
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Publisher
United States: American Chemical Society
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Language
English
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Publisher
United States: American Chemical Society
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Scope and Contents
Contents
The inefficient translocation of proteins across biological membranes limits their application as potential therapeutics and research tools. In many cases, the translocation of a protein involves two discrete steps: uptake into the endocytic pathway and endosomal escape. Certain charged or amphiphilic molecules can achieve high protein uptake, but...
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Full title
HOPS-Dependent Endosomal Escape Demands Protein Unfolding
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TN_cdi_doaj_primary_oai_doaj_org_article_18471f915d2747cabc245b87e7164be4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_18471f915d2747cabc245b87e7164be4
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ISSN
2374-7943
E-ISSN
2374-7951
DOI
10.1021/acscentsci.4c00016