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Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_18c9b4bc2d6a40a58f92ba99e8020ab8

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

About this item

Full title

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-01, Vol.8 (1), p.13993-13993, Article 13993

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Na
+
/H
+
antiporters are found in all kingdoms of life and exhibit catalysis rates that are among the fastest of all known secondary-active transporters. Here we combine ion mobility mass spectrometry and molecular dynamics simulations to study the conformational stability and lipid-binding properties of the Na
+
/H
+
excha...

Alternative Titles

Full title

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_18c9b4bc2d6a40a58f92ba99e8020ab8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_18c9b4bc2d6a40a58f92ba99e8020ab8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms13993