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Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19876507babc459ea8e2d3481a7a455c

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

About this item

Full title

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

Publisher

Cambridge: eLife Science Publications, Ltd

Journal title

eLife, 2022-09, Vol.11

Language

English

Formats

Publication information

Publisher

Cambridge: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The type VI secretion system (T6SS) is used by bacteria to deliver toxic effectors directly into target cells. Most T6SSs mediate antibacterial activities, whereas the potential anti-eukaryotic role of T6SS remains understudied. Here, we found a
Vibrio
T6SS that delivers two novel effectors into mammalian host immune cells. We showed that the...

Alternative Titles

Full title

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_19876507babc459ea8e2d3481a7a455c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19876507babc459ea8e2d3481a7a455c

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.82766

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