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ArticlesPeer ReviewedFull Text
The diverse role of RIP kinases in necroptosis and inflammation
Author / Creator:Silke, John ; Rickard, James A ; Gerlic, Motti
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2015-07, Vol.16 (7), p.689-697
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Flipping the dogma – phosphatidylserine in non-apoptotic cell death
Author / Creator:Shlomovitz, Inbar ; Speir, Mary ; Gerlic, Motti
Publisher:England: BioMed Central Ltd
Journal title:Cell communication and signaling, 2019-10, Vol.17 (1), p.139-12, Article 139
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A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
Author / Creator:Fridman, Chaya M. ; Keppel, Kinga ; Gerlic, Motti ; Bosis, Eran ; Salomon, Dor
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.1085-1085, Article 1085
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Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model
Author / Creator:Erlich, Ziv ; Shlomovitz, Inbar ; Edry-Botzer, Liat ; Cohen, Hadar ; Frank, Daniel ; Wang, Hanqing ; Lew, Andrew M. ; Lawlor, Kate E. ; Zhan, Yifan ; Vince, James E. ; Gerlic, Motti
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-04, Vol.20 (4), p.397-406
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NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis
Author / Creator:Ershaid, Nour ; Sharon, Yoray ; Doron, Hila ; Raz, Yael ; Shani, Ophir ; Cohen, Noam ; Monteran, Lea ; Leider-Trejo, Leonor ; Ben-Shmuel, Amir ; Yassin, Muhammad ; Gerlic, Motti ; Ben-Baruch, Adit ; Pasmanik-Chor, Metsada ; Apte, Roni ; Erez, Neta
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4375-15, Article 4375
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ArticlesPeer ReviewedFull Text
Phosphatidylserine externalization, “necroptotic bodies” release, and phagocytosis during necroptosis
Author / Creator:Zargarian, Sefi ; Shlomovitz, Inbar ; Erlich, Ziv ; Hourizadeh, Aria ; Ofir-Birin, Yifat ; Croker, Ben A. ; Regev-Rudzki, Neta ; Edry-Botzer, Liat ; Gerlic, Motti
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2017-06, Vol.15 (6), p.e2002711-e2002711
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ArticlesPeer ReviewedFull Text
Proteomic analysis of necroptotic extracellular vesicles
Author / Creator:Shlomovitz, Inbar ; Erlich, Ziv ; Arad, Gali ; Edry-Botzer, Liat ; Zargarian, Sefi ; Cohen, Hadar ; Manko, Tal ; Ofir-Birin, Yifat ; Cooks, Tomer ; Regev-Rudzki, Neta ; Gerlic, Motti
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2021-11, Vol.12 (11), p.1059-1059, Article 1059
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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
Author / Creator:Lawlor, Kate E. ; Khan, Nufail ; Mildenhall, Alison ; Gerlic, Motti ; Croker, Ben A. ; D’Cruz, Akshay A. ; Hall, Cathrine ; Kaur Spall, Sukhdeep ; Anderton, Holly ; Masters, Seth L. ; Rashidi, Maryam ; Wicks, Ian P. ; Alexander, Warren S. ; Mitsuuchi, Yasuhiro ; Benetatos, Christopher A. ; Condon, Stephen M. ; Wong, W. Wei-Lynn ; Silke, John ; Vaux, David L. ; Vince, James E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-02, Vol.6 (1), p.6282-6282, Article 6282
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Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors
Author / Creator:Cohen, Hadar ; Baram, Noam ; Fridman, Chaya Mushka ; Edry-Botzer, Liat ; Salomon, Dor ; Gerlic, Motti
Publisher:Cambridge: eLife Science Publications, Ltd
Journal title:eLife, 2022-09, Vol.11
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Mechanisms of RIPK3‐induced inflammation
Author / Creator:Shlomovitz, Inbar ; Zargrian, Sefi ; Gerlic, Motti
Publisher:England: Nature Publishing Group
Journal title:Immunology and cell biology, 2017-02, Vol.95 (2), p.166-172
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Rapid seroconversion and persistent functional IgG antibodies in severe COVID-19 patients correlates with an IL-12p70 and IL-33 signature
Author / Creator:Munitz, Ariel ; Edry-Botzer, L. ; Itan, M. ; Tur-Kaspa, R. ; Dicker, D. ; Marcoviciu, D. ; Goren, M. G. ; Mor, M. ; Lev, S. ; Gottesman, T. ; Muhsen, K. ; Cohen, D. ; Stein, M. ; Qimron, U. ; Freund, N. T. ; Wine, Y. ; Gerlic, Motti
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-02, Vol.11 (1), p.3461-3461, Article 3461
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Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors
Author / Creator:Sisquella, Xavier ; Ofir-Birin, Yifat ; Pimentel, Matthew A. ; Cheng, Lesley ; Abou Karam, Paula ; Sampaio, Natália G. ; Penington, Jocelyn Sietsma ; Connolly, Dympna ; Giladi, Tal ; Scicluna, Benjamin J. ; Sharples, Robyn A. ; Waltmann, Andreea ; Avni, Dror ; Schwartz, Eli ; Schofield, Louis ; Porat, Ziv ; Hansen, Diana S. ; Papenfuss, Anthony T. ; Eriksson, Emily M. ; Gerlic, Motti ; Hill, Andrew F. ; Bowie, Andrew G. ; Regev-Rudzki, Neta
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-12, Vol.8 (1), p.1985-15, Article 1985
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ArticlesPeer ReviewedFull Text
The coral pathogen Vibrio coralliilyticus uses a T6SS to secrete a group of novel anti-eukaryotic effectors that contribute to virulence
Author / Creator:Mass, Shir ; Cohen, Hadar ; Podicheti, Ram ; Rusch, Douglas B. ; Gerlic, Motti ; Ushijima, Blake ; van Kessel, Julia C. ; Bosis, Eran ; Salomon, Dor
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2024-09, Vol.22 (9), p.e3002734
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NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease
Author / Creator:Tye, Hazel ; Yu, Chien-Hsiung ; Simms, Lisa A. ; de Zoete, Marcel R. ; Kim, Man Lyang ; Zakrzewski, Martha ; Penington, Jocelyn S. ; Harapas, Cassandra R. ; Souza-Fonseca-Guimaraes, Fernando ; Wockner, Leesa F. ; Preaudet, Adele ; Mielke, Lisa A. ; Wilcox, Stephen A. ; Ogura, Yasunori ; Corr, Sinead C. ; Kanojia, Komal ; Kouremenos, Konstantinos A. ; De Souza, David P. ; McConville, Malcolm J. ; Flavell, Richard A. ; Gerlic, Motti ; Kile, Benjamin T. ; Papenfuss, Anthony T. ; Putoczki, Tracy L. ; Radford-Smith, Graham L. ; Masters, Seth L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-09, Vol.9 (1), p.3728-11, Article 3728
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Assessing toxicity and competitive fitness of Vibrio isolates from coastal waters in Israel
Author / Creator:Kanarek, Katarzyna ; Keppel, Kinga ; Cohen, Hadar ; Fridman, Chaya Mushka ; Gerlic, Motti ; Salomon, Dor
Publisher:United States: American Society for Microbiology
Journal title:mSphere, 2025-04, Vol.10 (4), p.e0002525
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Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation
Author / Creator:Speir, Mary ; Nowell, Cameron J. ; Chen, Alyce A. ; O’Donnell, Joanne A. ; Shamie, Isaac S. ; Lakin, Paul R. ; D’Cruz, Akshay A. ; Braun, Roman O. ; Babon, Jeff J. ; Lewis, Rowena S. ; Bliss-Moreau, Meghan ; Shlomovitz, Inbar ; Wang, Shu ; Cengia, Louise H. ; Stoica, Anca I. ; Hakem, Razq ; Kelliher, Michelle A. ; O’Reilly, Lorraine A. ; Patsiouras, Heather ; Lawlor, Kate E. ; Weller, Edie ; Lewis, Nathan E. ; Roberts, Andrew W. ; Gerlic, Motti ; Croker, Ben A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2020-01, Vol.21 (1), p.54-64
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Melanoma Cells from Different Patients Differ in Their Sensitivity to Alpha Radiation-Mediated Killing, Sensitivity Which Correlates with Cell Nuclei Area and Double Strand Breaks
Author / Creator:Levy, Or I. ; Altaras, Anat ; Binyamini, Lior ; Sagi-Assif, Orit ; Izraely, Sivan ; Cooks, Tomer ; Kobiler, Oren ; Gerlic, Motti ; Kelson, Itzhak ; Witz, Isaac P. ; Keisari, Yona
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2024-11, Vol.16 (22), p.3804
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Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation
Author / Creator:Gerlic, Motti ; Faustin, Benjamin ; Postigo, Antonio ; Yu, Eric Chi-Wang ; Proell, Martina ; Gombosuren, Naran ; Krajewska, Maryla ; Flynn, Rachel ; Croft, Michael ; Way, Michael ; Satterthwait, Arnold ; Liddington, Robert C. ; Salek-Ardakani, Shahram ; Matsuzawa, Shu-ichi ; Reed, John C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (19), p.7808-7813
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Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome
Author / Creator:Cohen, Hadar ; Baram, Noam ; Edry-Botzer, Liat ; Munitz, Ariel ; Salomon, Dor ; Gerlic, Motti
Publisher:United States: Taylor & Francis
Journal title:Emerging microbes & infections, 2020-01, Vol.9 (1), p.278-290
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ArticlesPeer ReviewedFull Text
A healthy appetite for Toxoplasma at the cellular level
Author / Creator:Gerlic, Motti ; Masters, Seth L
Publisher:United States: Nature Publishing Group
Journal title:Immunology and cell biology, 2014-11, Vol.92 (10), p.813-814
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Showing 1 to 20 of 32 results

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The diverse role of RIP kinases in necroptosis and inflammation

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Flipping the dogma – phosphatidylserine in non-apoptotic cell death

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A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors

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Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model

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NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis

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Phosphatidylserine externalization, “necroptotic bodies” release, and phagocytosis during necroptosis

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Proteomic analysis of necroptotic extracellular vesicles

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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

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Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

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Mechanisms of RIPK3‐induced inflammation

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Rapid seroconversion and persistent functional IgG antibodies in severe COVID-19 patients correlates with an IL-12p70 and IL-33 signature

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Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

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The coral pathogen Vibrio coralliilyticus uses a T6SS to secrete a group of novel anti-eukaryotic effectors that contribute to virulence

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NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

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Assessing toxicity and competitive fitness of Vibrio isolates from coastal waters in Israel

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Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation

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Melanoma Cells from Different Patients Differ in Their Sensitivity to Alpha Radiation-Mediated Killing, Sensitivity Which Correlates with Cell Nuclei Area and Double Strand Breaks

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Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation

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Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome

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A healthy appetite for Toxoplasma at the cellular level

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