A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's di...
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter
About this item
Full title
Author / Creator
LaBarbera, Kelsie M , Sheline, Yvette I , Izzo, Nicholas J , Yuede, Carla M , Waybright, Lora , Yurko, Raymond , Edwards, Hannah M , Gardiner, Woodrow D , Blennow, Kaj , Zetterberg, Henrik , Börjesson-Hanson, Anne , Morgan, Roger , Davis, Charles S , Guttendorf, Robert J , Schneider, Lon S , DeKosky, Steven , LeVine, 3rd, Harry , Grundman, Michael , Caggiano, Anthony O , Cirrito, John R , Catalano, Susan M and Hamby, Mary E
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
More information
Scope and Contents
Contents
In support of this, Aβ oligomer reduction in an AD mouse model leads to memory preservation [2, 3], and clinical benefit was in trials of lecanemab, which targets Aβ oligomers and protofibrils [4], in AD patients, encouraging the continued development of Aβ oligomer-targeting therapies. Given the semi-quantitative nature of the Aβ oligomer assays,...
Alternative Titles
Full title
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter
Authors, Artists and Contributors
Author / Creator
Sheline, Yvette I
Izzo, Nicholas J
Yuede, Carla M
Waybright, Lora
Yurko, Raymond
Edwards, Hannah M
Gardiner, Woodrow D
Blennow, Kaj
Zetterberg, Henrik
Börjesson-Hanson, Anne
Morgan, Roger
Davis, Charles S
Guttendorf, Robert J
Schneider, Lon S
DeKosky, Steven
LeVine, 3rd, Harry
Grundman, Michael
Caggiano, Anthony O
Cirrito, John R
Catalano, Susan M
Hamby, Mary E
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_19f084bea18e49d6b821e4355697a8ba
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19f084bea18e49d6b821e4355697a8ba
Other Identifiers
ISSN
2047-9158
E-ISSN
2047-9158
DOI
10.1186/s40035-023-00358-w
