HMGB1 coordinates SASP‐related chromatin folding and RNA homeostasis on the path to senescence
HMGB1 coordinates SASP‐related chromatin folding and RNA homeostasis on the path to senescence
About this item
Full title
Author / Creator
Sofiadis, Konstantinos , Josipovic, Natasa , Nikolic, Milos , Kargapolova, Yulia , Übelmesser, Nadine , Varamogianni‐Mamatsi, Vassiliki , Zirkel, Anne , Papadionysiou, Ioanna , Loughran, Gary , Keane, James , Michel, Audrey , Gusmao, Eduardo G , Becker, Christian , Altmüller, Janine , Georgomanolis, Theodore , Mizi, Athanasia and Papantonis, Argyris
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Spatial organization and gene expression of mammalian chromosomes are maintained and regulated in conjunction with cell cycle progression. This is perturbed once cells enter senescence and the highly abundant HMGB1 protein is depleted from nuclei to act as an extracellular proinflammatory stimulus. Despite its physiological importance, we know litt...
Alternative Titles
Full title
HMGB1 coordinates SASP‐related chromatin folding and RNA homeostasis on the path to senescence
Authors, Artists and Contributors
Author / Creator
Josipovic, Natasa
Nikolic, Milos
Kargapolova, Yulia
Übelmesser, Nadine
Varamogianni‐Mamatsi, Vassiliki
Zirkel, Anne
Papadionysiou, Ioanna
Loughran, Gary
Keane, James
Michel, Audrey
Gusmao, Eduardo G
Becker, Christian
Altmüller, Janine
Georgomanolis, Theodore
Mizi, Athanasia
Papantonis, Argyris
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1c45f529d5074d11a54d216e9bc18458
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1c45f529d5074d11a54d216e9bc18458
Other Identifiers
ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.20209760
