Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice
Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Meiotic crossovers result from homology-directed repair of DNA double-strand breaks (DSBs). Unlike yeast and plants, where DSBs are generated near gene promoters, in many vertebrates DSBs are enriched at hotspots determined by the DNA binding activity of the rapidly evolving zinc finger array of PRDM9 (PR domain zinc finger protein 9). PRDM9 subseq...
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Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice
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TN_cdi_doaj_primary_oai_doaj_org_article_1cd9ae76ec8f4b498b795ac0bd86cca7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1cd9ae76ec8f4b498b795ac0bd86cca7
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.53360
