HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypo...
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury
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Author / Creator
Zhao, Min , Wang, Shaoting , Zuo, Anna , Zhang, Jiaxing , Wen, Weiheng , Jiang, Weiqiang , Chen, Hong , Liang, Donghui , Sun, Jia and Wang, Ming
Publisher
England: BioMed Central
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
Endothelial cell (EC) injury accelerates the progression of diabetic macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible factor-1 alpha (HIF-1α) is an important hypoxia regulatory protein. Our previous studies showed that high-glucose and hypoxic conditions could upregulate HIF-1α expression and enhance EC inf...
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Full title
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1d0d9fb1641b43b7b1f6102544f5d312
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1d0d9fb1641b43b7b1f6102544f5d312
Other Identifiers
ISSN
1425-8153
E-ISSN
1689-1392
DOI
10.1186/s11658-021-00283-8
