The white matter is a pro-differentiative niche for glioblastoma
The white matter is a pro-differentiative niche for glioblastoma
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Author / Creator
Brooks, Lucy J. , Clements, Melanie P. , Burden, Jemima J. , Kocher, Daniela , Richards, Luca , Devesa, Sara Castro , Zakka, Leila , Woodberry, Megan , Ellis, Michael , Jaunmuktane, Zane , Brandner, Sebastian , Morrison, Gillian , Pollard, Steven M. , Dirks, Peter B. , Marguerat, Samuel and Parrinello, Simona
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Glioblastomas are hierarchically organised tumours driven by glioma stem cells that retain partial differentiation potential. Glioma stem cells are maintained in specialised microenvironments, but whether, or how, they undergo lineage progression outside of these niches remains unclear. Here we identify the white matter as a differentiative niche f...
Alternative Titles
Full title
The white matter is a pro-differentiative niche for glioblastoma
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TN_cdi_doaj_primary_oai_doaj_org_article_1dfd4c8671124520ac4d6ba779864aae
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1dfd4c8671124520ac4d6ba779864aae
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22225-w
